Results 51 to 60 of about 1,119,255 (298)
Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene
Genetics Research, 2022 POLD1 (DNA polymerase delta 1, catalytic subunit) is a protein-coding gene that encodes the large catalytic subunit (POLD1/p125) of the DNA polymerase delta (Polδ) complex.
Md. Nazmul Islam Bappy +9 more
doaj +1 more source
Collective action framing genetic engineering resistance in New Zealand [PDF]
, 2011 The genetic engineering resistance movement in New Zealand constructed strategic and meaningful interpretations of why the genetic engineering technique is problematic and what can be done about it.
Tucker, C
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
In-Silico Exploration of Plant Metabolites as Potential Remedies of Norovirus
Advances in Virology, 2022 Research is still being carried out to develop specific medications or vaccinations to fight norovirus, a key contributor to foodborne illness. This study evaluated certain plant-based active chemicals as prospective candidates for such treatments using ...
Zenifer Alam +6 more
doaj +1 more source
A service oriented architecture for engineering design [PDF]
, 2004 Decision making in engineering design can be effectively addressed by using genetic algorithms to solve multi-objective problems. These multi-objective genetic algorithms (MOGAs) are well suited to implementation in a Service Oriented Architecture ...
Fleming, P.J., Shenfield, A.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
International Journal of Genomics, 2023 Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms of
Fayeza Sadia Laskar +6 more
doaj +1 more source
Should Parents Genetically Engineer their Children? [PDF]
, 2019 Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful, albeit unrealistic. However, recent scientific developments in genetic engineering, namely CRISPR/Cas bring the question into public ...
Veit, Walter
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Unstandard Standardization: The Case of Biology [PDF]
, 2010 How applicable are the approaches adopted by information and communication technology standards-setting organizations to biological standards? Most engineering-based industries construct products from standard, well understood components.
Rai, Arti K.
core +1 more source