Results 51 to 60 of about 1,062,704 (335)
Should Parents Genetically Engineer their Children? [PDF]
, 2019 Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful, albeit unrealistic. However, recent scientific developments in genetic engineering, namely CRISPR/Cas bring the question into public ...
Veit, Walter
core
Partial Trajectory: The Story of the Altered Nuclear Transfer-Oocyte Assisted Reprogramming (ANT-OAR) Proposal [PDF]
, 2007 This essay aims to tell the story of the “altered nuclear transfer-oocyte assisted reprogramming,” or ANT-OAR, proposal—from its conception by Professor William Hurlbut of the President’s Council on Bioethics—to its adoption and promotion by a group of ...
Byrnes, W. Malcolm
core +2 more sources
Photothermal Genetic Engineering [PDF]
ACS Nano, 2012 Optical methods for manipulation of cellular function have enabled deconstruction of genetic and neural circuits in vitro and in vivo. Plasmonic gold nanomaterials provide an alternative platform for external optical manipulation of genetic circuits.
Deisseroth, Karl +1 more
openaire +4 more sources
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Unstandard Standardization: The Case of Biology [PDF]
, 2010 How applicable are the approaches adopted by information and communication technology standards-setting organizations to biological standards? Most engineering-based industries construct products from standard, well understood components.
Rai, Arti K.
core +1 more source
Modeling viral infectious diseases and development of antiviral therapies using human induced pluripotent stem cell-derived systems [PDF]
, 2015 The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Barzon, Luisa +6 more
core +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
2D multi-objective placement algorithm for free-form components [PDF]
, 2009 This article presents a generic method to solve 2D multi-objective placement problem for free-form components. The proposed method is a relaxed placement technique combined with an hybrid algorithm based on a genetic algorithm and a separation algorithm.
Bennis, Fouad +3 more
core +2 more sources
Genetic algorithms with memory- and elitism-based immigrants in dynamic environments [PDF]
, 2008 Copyright @ 2008 by the Massachusetts Institute of TechnologyIn recent years the genetic algorithm community has shown a growing interest in studying dynamic optimization problems. Several approaches have been devised.
Shengxiang Yang, Trojanowski K.
core +3 more sources
Plant Genetic Resources: Selected Issues from Genetic Erosion to Genetic Engineering
Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2008 Plant Genetic Resources (PGR) continue to play an important role in the development of agriculture. The following aspects receive a special consideration:1. Definition. The term was coined in 1970.
Karl Hammer, Yifru Teklu
doaj