Results 61 to 70 of about 723,030 (329)

Scaling Genetic Programming for Source Code Modification [PDF]

open access: yesarXiv, 2012
In Search Based Software Engineering, Genetic Programming has been used for bug fixing, performance improvement and parallelisation of programs through the modification of source code. Where an evolutionary computation algorithm, such as Genetic Programming, is to be applied to similar code manipulation tasks, the complexity and size of source code for
arxiv  

Genetic Engineering Algorithm (GEA): An Efficient Metaheuristic Algorithm for Solving Combinatorial Optimization Problems [PDF]

open access: yesarXiv, 2023
Genetic Algorithms (GAs) are known for their efficiency in solving combinatorial optimization problems, thanks to their ability to explore diverse solution spaces, handle various representations, exploit parallelism, preserve good solutions, adapt to changing dynamics, handle combinatorial diversity, and provide heuristic search.
arxiv  

A service oriented architecture for engineering design [PDF]

open access: yes, 2004
Decision making in engineering design can be effectively addressed by using genetic algorithms to solve multi-objective problems. These multi-objective genetic algorithms (MOGAs) are well suited to implementation in a Service Oriented Architecture ...
Fleming, P.J., Shenfield, A.
core  

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Plant Genetic Resources: Selected Issues from Genetic Erosion to Genetic Engineering

open access: yesJournal of Agriculture and Rural Development in the Tropics and Subtropics, 2008
Plant Genetic Resources (PGR) continue to play an important role in the development of agriculture. The following aspects receive a special consideration:1. Definition. The term was coined in 1970.
Karl Hammer, Yifru Teklu
doaj  

It's the Journey Not the Destination: Building Genetic Algorithms Practitioners Can Trust [PDF]

open access: yesarXiv, 2020
Genetic algorithms have been developed for decades by researchers in academia and perform well in engineering applications, yet their uptake in industry remains limited. In order to understand why this is the case, the opinions of users of engineering design tools were gathered.
arxiv  

Should Parents Genetically Engineer their Children? [PDF]

open access: yes, 2019
Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful, albeit unrealistic. However, recent scientific developments in genetic engineering, namely CRISPR/Cas bring the question into public ...
Veit, Walter
core  

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Genetic Algorithms and its use with back-propagation network [PDF]

open access: yesAIN Shams University, Faculty of Engineering Scientific Bulletin, Volume 35, Issue 3, pp 337-348 (2000), 2014
Genetic algorithms are considered as one of the most efficient search techniques. Although they do not offer an optimal solution, their ability to reach a suitable solution in considerably short time gives them their respectable role in many AI techniques. This work introduces genetic algorithms and describes their characteristics.
arxiv  

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

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