Results 141 to 150 of about 17,950,884 (399)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Evaluation of Cancer-Based Criteria for Use in Mainstream BRCA1 and BRCA2 Genetic Testing in Patients With Breast Cancer

JAMA Network Open, 2019
Key Points Question How can BRCA1 and BRCA2 gene testing in patients with cancer be increased? Findings In this quality improvement study of 1184 individuals, 5 cancer-based criteria with a 10% mutation detection rate were used by the cancer team to ...
Z. Kemp, Alice Turnbull, Shawn E. Yost, S. Seal, S. Mahamdallie, E. Poyastro-Pearson, M. Warren-Perry, A. Eccleston, Min-Min Tan, S. Teo, N. Turner, Ann Strydom, A. George, N. Rahman   +13 more
semanticscholar   +1 more source

Efeito da interação reprodutor x rebanho sobre as produções de leite e de gordura na raça Pardo-Suíça Effects of sire x herd interaction on milk and fat yields in Brown-Swiss herds

Revista Brasileira de Zootecnia, 2005
Dados de 4.959 lactações de 2.414 vacas da raça Pardo-Suíça, filhas de 70 reprodutores, distribuídos em 51 rebanhos, foram utilizados para se estimar o componente de variância para a interação reprodutor x rebanho das produções de leite e de gordura e ...
Mirella Leme Franco Geraldini Sirol, Ricardo Frederico Euclydes, Robledo de Almeida Torres, Paulo Sávio Lopes, Carmen Silva Pereira, Cláudio Vieira Araújo, Francisco Palma Rennó   +6 more
doaj   +1 more source

'On the Application of Hierarchical Coevolutionary Genetic Algorithms: Recombination and Evaluation Partners' [PDF]

, 2003
This paper examines the use of a hierarchical coevolutionary genetic algorithm under different partnering strategies. Cascading clusters of sub-populations are built from the bottom up, with higher-level sub-populations optimising larger parts of the ...
Aickelin, Uwe, Bull, Larry
core   +5 more sources

Twin Zygosity Diagnosis by Genetic Systems—An Efficiency Evaluation A Comment to a Paper by Selvin [1977] [PDF]

, 1979
Ranajit Chakraborty
openalex   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Pollen–pistil interactions in divergent wide crosses lead to spatial and temporal pre-fertilization reproductive barrier in flax (Linum usitatissimum L.)

Scientific Reports
Linseed, has been a source of natural fiber for textile industries since its domestication. However, despite being the potential source of trait reservoir, the use of Linum wild genetic resources for the improvement of economic traits are not exploited ...
Vijaykumar Kailasrao Raut, Aneeta Yadav, Vikender Kaur, Mahesh Rao, Pooja Pathania, Dhammaprakash Wankhede, Mamta Singh, Gyanendra Pratap Singh   +7 more
doaj   +1 more source

Estimação de parâmetros genéticos utilizando-se a produção de leite no dia do controle em primeiras lactações de vacas da raça Jersey Estimation of genetic parameters for test day milk yield of first lactation Jersey cows using repeatability and random regression models

Revista Brasileira de Zootecnia, 2006
Registros da produção de leite de 3.531 controles de 620 primíparas da raça Jersey foram utilizados para a estimação dos componentes de covariância e dos parâmetros genéticos para a produção de leite por meio dos modelos de repetibilidade e de regressão ...
Nelson José Laurino Dionello, Carlos Alberto Soares da Silva, Claudio Napolis Costa, Jaime Araújo Cobuci   +3 more
doaj   +1 more source

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

Evaluation of genetic causes of cardiomyopathy in childhood [PDF]

Cardiology in the Young, 2015
AbstractCardiomyopathy frequently has a genetic basis. In adults, mutations in genes encoding components of the sarcomere, cytoskeleton, or desmosome are frequent genetic causes of cardiomyopathy. Although children share these causes, ~30% of children have an underlying metabolic, syndromic, or neuromuscular condition causing their cardiomyopathy ...
openaire   +4 more sources