Results 31 to 40 of about 4,927,397 (250)

How Symbiosis Can Guide Evolution

open access: yes, 1999
Hinton and Nowlan have demonstrated a model of how lifetime plasticity can guide evolution. They show how acquired traits change the shape of the reward landscape in which subsequent genetic variation takes place, and in so doing encourage the discovery ...
Pollack, Jordan B., Watson, Richard A.
core   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Fused in sarcoma (FUS) inhibits milk production efficiency in mammals

open access: yesNature Communications
Efficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao   +15 more
doaj   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom   +15 more
wiley   +1 more source

Genomic evidence for the evolution of Streptococcus equi : host restriction, increased virulence, and genetic exchange with human pathogens [PDF]

open access: yes, 2009
The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered. Streptococcus equi subspecies equi (S.
Parkhill Julian   +118 more
core   +1 more source

Single-cell expression profiling of bat wing development

open access: yesNature Communications
Bats are the only true-flight mammals, with wings formed by elongated digits and wing membranes. Despite the uniqueness, the cellular and molecular aspects of bat wing development remain largely unknown. Here, we use single-cell transcriptomic sequencing
Xue Lyu   +7 more
doaj   +1 more source

Molecular convergence and transgenic evidence suggest a single origin of laryngeal echolocation in bats

open access: yesiScience, 2022
Summary: The laryngeal echolocation is regarded as one of the conspicuous traits that play major roles in flourishing bats. Whether the laryngeal echolocation in bats originated once, however, is still controversial.
Zhen Liu   +8 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld   +5 more
wiley   +1 more source

Experimental evidence for cancer resistance in a bat species

open access: yesNature Communications
Mammals exhibit different rates of cancer, with long-lived species generally showing greater resistance. Although bats have been suggested to be resistant to cancer due to their longevity, this has yet to be systematically examined.
Rong Hua   +8 more
doaj   +1 more source

Mountains too high and valleys too deep drive population structuring and demographics in a Qinghai–Tibetan Plateau frog Nanorana pleskei (Dicroglossidae)

open access: yesEcology and Evolution, 2017
Pleistocene glacial–interglacial climatic oscillations greatly shaped the current genetic structure of many species. However, geographic features may influence the impact of climatic cycling.
Weiwei Zhou   +6 more
doaj   +1 more source

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