Results 41 to 50 of about 1,500,618 (293)

Cultural evolution of genetic heritability [PDF]

Behavioral and Brain Sciences, 2020
Abstract Behavioral genetics and cultural evolution have both revolutionized our understanding of human behavior – largely independent of each other. Here, we reconcile these two fields under a dual inheritance framework, offering a more nuanced understanding of the interaction between genes and culture.
Ryutaro Uchiyama, Rachel Spicer, Michael Muthukrishna   +2 more
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Fused in sarcoma (FUS) inhibits milk production efficiency in mammals

Nature Communications
Efficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao, Jipeng Huang, Hui Wang, Guolei Wang, Xu Yang, Mei Cheng, Changjie Sun, Li Zou, Qin Yang, Dandan Zhang, Zhen Liu, Xuelong Jiang, Lei Shi, Peng Shi, Baowei Han, Baowei Jiao   +15 more
doaj   +1 more source

Non-equilibrium time dynamics of genetic evolution

, 2018
Biological systems are typically highly open, non-equilibrium systems that are very challenging to understand from a statistical mechanics perspective.
Birman, Liev, Byrnes, Tim, Nehme, Samer Intissar, Radhakrishnan, Chandrashekar, Rastegar-Sedehi, Hamid-Reza, Velasquez, Paula   +5 more
core   +1 more source

Mother nature's tolerant ways: why non-genetic inheritance has nothing to do with evolution [PDF]

, 2007
Recently a number of theorists have suggested that evolution can use non-genetic or environmental inheritance to pass on adaptations (e.g. Mameli, 2004).
Dickins, BJA, Dickins, TE
core   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Experimental evidence for cancer resistance in a bat species

Nature Communications
Mammals exhibit different rates of cancer, with long-lived species generally showing greater resistance. Although bats have been suggested to be resistant to cancer due to their longevity, this has yet to be systematically examined.
Rong Hua, Yuan-Shuo Ma, Lu Yang, Jun-Jun Hao, Qin-Yang Hua, Lu-Ye Shi, Xiao-Qing Yao, Hao-Yu Zhi, Zhen Liu   +8 more
doaj   +1 more source

Mountains too high and valleys too deep drive population structuring and demographics in a Qinghai–Tibetan Plateau frog Nanorana pleskei (Dicroglossidae)

Ecology and Evolution, 2017
Pleistocene glacial–interglacial climatic oscillations greatly shaped the current genetic structure of many species. However, geographic features may influence the impact of climatic cycling.
Weiwei Zhou, Jieqiong Jin, Jun Wu, Hongman Chen, Junxiao Yang, Robert W. Murphy, Jing Che   +6 more
doaj   +1 more source

Correction to: FastMM: an efficient toolbox for personalized constraint-based metabolic modeling

BMC Bioinformatics, 2020
An amendment to this paper has been published and can be accessed via the original article.
Gong-Hua Li, Shaoxing Dai, Feifei Han, Wenxing Li, Jingfei Huang, Wenzhong Xiao   +5 more
doaj   +1 more source