Results 31 to 40 of about 186,500 (263)
Evolution Letters, 2019 Sex differences in morphology, physiology, development, and behavior are widespread, yet the sexes inherit nearly identical genomes, causing most traits to exhibit strong and positive cross‐sex genetic correlations.
Tim Connallon, Genevieve Matthews
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Predicting the evolution of sex on complex fitness landscapes.
PLoS Computational Biology, 2009 Most population genetic theories on the evolution of sex or recombination are based on fairly restrictive assumptions about the nature of the underlying fitness landscapes.
Dusan Misevic +2 more
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Simple Genetic Algorithms with Linear Fitness
Evolutionary Computation, 1994 A general form of stochastic search is described (random heuristic search), and some of its general properties are proved. This provides a framework in which the simple genetic algorithm (SGA) is a special case. The framework is used to illuminate relationships between seemingly different probabilistic perspectives of SGA behavior.
Michael D. Vose, Alden H. Wright
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Direct selection on genetic robustness revealed in the yeast transcriptome. [PDF]
PLoS ONE, 2007 Evolutionary theory predicts that organisms should evolve the ability to produce high fitness phenotypes in the face of environmental disturbances (environmental robustness) or genetic mutations (genetic robustness).
Stephen R Proulx +2 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Population bottlenecks constrain host microbiome diversity and genetic variation impeding fitness.
PLoS Genetics, 2022 It is becoming increasingly clear that microbial symbionts influence key aspects of their host's fitness, and vice versa. This may fundamentally change our thinking about how microbes and hosts interact in influencing fitness and adaptation to changing ...
Michael Ørsted +3 more
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Sex Reversal and Performance in Fitness-Related Traits During Early Life in Agile Frogs
Frontiers in Ecology and Evolution, 2021 Sex reversal is a mismatch between genetic sex (sex chromosomes) and phenotypic sex (reproductive organs and secondary sexual traits). It can be induced in various ectothermic vertebrates by environmental perturbations, such as extreme temperatures or ...
Veronika Bókony +10 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Evolution of genetic redundancy: the relevance of complexity in genotype–phenotype mapping
New Journal of Physics, 2014 Despite its ubiquity among organisms, genetic redundancy is presumed to reduce total population fitness and is therefore unlikely to evolve. This study evaluates an evolutionary model with high-dimensional genotype–phenotype mapping (GPM) by applying a ...
Nen Saito +2 more
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