Results 51 to 60 of about 492,575 (295)
Evolutionary accessibility of modular fitness landscapes
A fitness landscape is a mapping from the space of genetic sequences, which is modeled here as a binary hypercube of dimension $L$, to the real numbers. We consider random models of fitness landscapes, where fitness values are assigned according to some ...
Krug, Joachim, Schmiegelt, Benjamin
core +1 more source
Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles +4 more
wiley +1 more source
Evolution of genetic redundancy: the relevance of complexity in genotype–phenotype mapping
Despite its ubiquity among organisms, genetic redundancy is presumed to reduce total population fitness and is therefore unlikely to evolve. This study evaluates an evolutionary model with high-dimensional genotype–phenotype mapping (GPM) by applying a ...
Nen Saito +2 more
doaj +1 more source
The Saudi genome project started in 2013 with a great hope to improve medical care and disease prevention. Among the genes are those related to nutrition and fitness that can optimize an individual’s lifestyle.
Faten Dhawi, Faisal Shehab Alotaibi
doaj +1 more source
Background Apomixis, the asexual reproduction through seeds, occurs in over 40 plant families and avoids the hidden cost of sex. Apomictic plants are thought to have an advantage in sparse populations and when colonizing new areas but may have a ...
Christian Sailer +4 more
doaj +1 more source
Evolutionary dynamics of tumor progression with random fitness values
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations,
Becskei +43 more
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Population genetic diversity and fitness in multiple environments
Background When a large number of alleles are lost from a population, increases in individual homozygosity may reduce individual fitness through inbreeding depression.
McGreevy Thomas J +8 more
doaj +1 more source
Optimal Portfolio Using a Genetic Algorithm [PDF]
Distributing the amount of money to invest in each stock of a portfolio, while maximizing profit and minimizing risk is key. This project applied the method of a genetic algorithm in order to select an optimal portfolio.
Reyes, Hector
core +1 more source
GENETIC BACKGROUND AND THE FITNESS OF ALLOZYMES [PDF]
ABSTRACT Experimental perturbations of gene frequency at the esterase-5 locus in Drosophila pseudoobscura were carried out in a series of population cages started with differing numbers of founder chromosomes. Cages founded with few chromosomes showed changes in gene frequency at the allozyme locus. Such changes were less marked in cages
J S, Jones, T, Yamazaki
openaire +2 more sources

