Results 51 to 60 of about 492,575 (295)

Evolutionary accessibility of modular fitness landscapes

open access: yes, 2013
A fitness landscape is a mapping from the space of genetic sequences, which is modeled here as a binary hypercube of dimension $L$, to the real numbers. We consider random models of fitness landscapes, where fitness values are assigned according to some ...
Krug, Joachim, Schmiegelt, Benjamin
core   +1 more source

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles   +4 more
wiley   +1 more source

Evolution of genetic redundancy: the relevance of complexity in genotype–phenotype mapping

open access: yesNew Journal of Physics, 2014
Despite its ubiquity among organisms, genetic redundancy is presumed to reduce total population fitness and is therefore unlikely to evolve. This study evaluates an evolutionary model with high-dimensional genotype–phenotype mapping (GPM) by applying a ...
Nen Saito   +2 more
doaj   +1 more source

Genetic screening for quality-of-life improvement and post–genetic testing consideration in Saudi Arabia

open access: yesFamily Medicine and Community Health, 2018
The Saudi genome project started in 2013 with a great hope to improve medical care and disease prevention. Among the genes are those related to nutrition and fitness that can optimize an individual’s lifestyle.
Faten Dhawi, Faisal Shehab Alotaibi
doaj   +1 more source

Apomixis and genetic background affect distinct traits in Hieracium pilosella L. grown under competition

open access: yesBMC Biology, 2021
Background Apomixis, the asexual reproduction through seeds, occurs in over 40 plant families and avoids the hidden cost of sex. Apomictic plants are thought to have an advantage in sparse populations and when colonizing new areas but may have a ...
Christian Sailer   +4 more
doaj   +1 more source

Evolutionary dynamics of tumor progression with random fitness values

open access: yes, 2010
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations,
Becskei   +43 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Population genetic diversity and fitness in multiple environments

open access: yesBMC Evolutionary Biology, 2010
Background When a large number of alleles are lost from a population, increases in individual homozygosity may reduce individual fitness through inbreeding depression.
McGreevy Thomas J   +8 more
doaj   +1 more source

Optimal Portfolio Using a Genetic Algorithm [PDF]

open access: yes, 2016
Distributing the amount of money to invest in each stock of a portfolio, while maximizing profit and minimizing risk is key. This project applied the method of a genetic algorithm in order to select an optimal portfolio.
Reyes, Hector
core   +1 more source

GENETIC BACKGROUND AND THE FITNESS OF ALLOZYMES [PDF]

open access: yesGenetics, 1974
ABSTRACT Experimental perturbations of gene frequency at the esterase-5 locus in Drosophila pseudoobscura were carried out in a series of population cages started with differing numbers of founder chromosomes. Cages founded with few chromosomes showed changes in gene frequency at the allozyme locus. Such changes were less marked in cages
J S, Jones, T, Yamazaki
openaire   +2 more sources

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