Results 1 to 10 of about 43,129 (160)
Adaptive Differential Evolution Algorithm Based on Fitness Landscape Characteristic
Mathematics, 2022 Differential evolution (DE) is a simple, effective, and robust algorithm, which has demonstrated excellent performance in dealing with global optimization problems.
Liming Zheng, Shiqi Luo
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Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape [PDF]
PLoS Biology, 2022 The fitness landscape represents the complex relationship between genotype or phenotype and fitness under a given environment, the structure of which allows the explanation and prediction of evolutionary trajectories.
Junichiro Iwasawa +5 more
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Fitness Landscapes of Functional RNAs [PDF]
Life, 2015 The notion of fitness landscapes, a map between genotype and fitness, was proposed more than 80 years ago. For most of this time data was only available for a few alleles, and thus we had only a restricted view of the whole fitness landscape.
Ádám Kun, Eörs Szathmáry
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IEEE Access, 2019 The no-wait flow shop scheduling problem (NWFSP) is one of the essential models in the manufacturing systems. In this paper, the fitness landscape of the factorial representation for NWFSP with the makespan criterion is studied. The encoding and decoding
Fuqing Zhao +5 more
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Competition-driven eco-evolutionary feedback reshapes bacteriophage lambda’s fitness landscape and enables speciation [PDF]
Nature CommunicationsA major challenge in evolutionary biology is explaining how populations navigate rugged fitness landscapes without getting trapped on local optima.
Michael B. Doud +5 more
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The plasmid-host fitness landscape: a new paradigm for predicting the fate of mobile resistance [PDF]
Applied and Environmental MicrobiologyThe widespread persistence of antimicrobial resistance (AMR) plasmids presents a fundamental challenge to microbial evolution, known as the “plasmid paradox”: if these plasmids cause fitness cost, why are they not eliminated by selection?
Hevar N. Abdulqadir
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Heterogeneity of the GFP fitness landscape and data-driven protein design [PDF]
eLife, 2022 Studies of protein fitness landscapes reveal biophysical constraints guiding protein evolution and empower prediction of functional proteins. However, generalisation of these findings is limited due to scarceness of systematic data on fitness landscapes ...
Louisa Gonzalez Somermeyer +9 more
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Searching the clinical fitness landscape.
PLoS ONE, 2012 Widespread unexplained variations in clinical practices and patient outcomes suggest major opportunities for improving the quality and safety of medical care.
Margaret J Eppstein +3 more
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Fitness Landscapes and Evolvability [PDF]
Evolutionary Computation, 2002 In this paper, we develop techniques based on evolvability statistics of the fitness land-scape surrounding sampled solutions. Averaging the measures over a sample of equal fitness solutions allows us to build up fitness evolvability portraits of the fitness land-scape, which we show can be used to compare both the ruggedness and neutrality in a set ...
Tom Smith +3 more
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eLife, 2022 Estimating the complex relationship between fitness and genotype or phenotype (i.e. the adaptive landscape) is one of the central goals of evolutionary biology.
Austin H Patton +4 more
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