Results 31 to 40 of about 49,034 (303)
Automatic differentiation and the optimization of differential equation models in biology
Frontiers in Ecology and Evolution, 2022 A computational revolution unleashed the power of artificial neural networks. At the heart of that revolution is automatic differentiation, which calculates the derivative of a performance measure relative to a large number of parameters. Differentiation
Steven A. Frank
doaj +1 more source
Analysis of epistatic interactions and fitness landscapes using a new geometric approach
BMC Evolutionary Biology, 2007 Background Understanding interactions between mutations and how they affect fitness is a central problem in evolutionary biology that bears on such fundamental issues as the structure of fitness landscapes and the evolution of sex.
Elena Santiago F +4 more
doaj +1 more source
Fitness Landscapes and Evolution [PDF]
, 1996 The concept of fitness is introduced, and a simple derivation of the Fundamental Theorem of Natural Selection (which states that the average fitness of a population increases if its variance is nonzero) is given. After a short discussion of the adaptative walk model, a short review is given of the quasispecies approach to molecular evolution and to the
openaire +2 more sources
Fitness costs associated with evolved herbicide resistance alleles in plants [PDF]
, 2009 Predictions based on evolutionary theory suggest that the adaptive value of evolved herbicide resistance alleles may be compromised by the existence of fitness costs.
Martin M. Vila‐Aiub +5 more
core +1 more source
'Sexercise': Working out heterosexuality in Jane Fonda’s fitness books [PDF]
, 2011 This is an Author's Accepted Manuscript of an article published in Leisure Studies, 30(2), 237 - 255, 2011, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/02614367.2010.523837.This paper explores the connection ...
Mansfield, L, Louise Mansfield
core +1 more source
Predictable properties of fitness landscapes induced by adaptational tradeoffs
eLife, 2020 Fitness effects of mutations depend on environmental parameters. For example, mutations that increase fitness of bacteria at high antibiotic concentration often decrease fitness in the absence of antibiotic, exemplifying a tradeoff between adaptation to ...
Suman G Das +4 more
doaj +1 more source
A Study of Fitness Landscapes for Neuroevolution [PDF]
2020 IEEE Congress on Evolutionary Computation (CEC), 2020 IEE CEC ...
Nuno M. Rodrigues +2 more
openaire +2 more sources
Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]
, 2012 Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
core +1 more source
PLoS Genetics, 2019 Characterizing the fitness landscape, a representation of fitness for a large set of genotypes, is key to understanding how genetic information is interpreted to create functional organisms.
Victoria O Pokusaeva +13 more
doaj +1 more source
Evolutionary accessibility of mutational pathways
, 2011 Functional effects of different mutations are known to combine to the total effect in highly nontrivial ways. For the trait under evolutionary selection (‘fitness’), measured values over all possible combinations of a set of mutations yield a fitness ...
J Arjan G M de Visser +9 more
core +1 more source