Results 131 to 140 of about 1,195,293 (349)

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Sheep breeding schemes utilising artificial insemination; large-scale simulation with a complex breeding goal

Animal, 2011
Alternative Norwegian sheep breeding schemes were evaluated by stochastic simulation of a breeding population with about 120 000 ewes, considering the gain for an aggregate genotype including nine traits and also the rate of inbreeding. The schemes were:
L.S. Eikje, L.R. Schaeffer, T. Ådnøy, G. Klemetsdal   +3 more
doaj  

Models to estimate genetic gain of soybean seed yield from annual multi-environment field trials. [PDF]

Theor Appl Genet, 2023
Krause MD, Piepho HP, Dias KOG, Singh AK, Beavis WD.   +4 more
europepmc   +1 more source

Biology of pelagic sea turtles: effects of marine debris [PDF]

, 1998
Objectives: 1. Quantify the sub-lethal effect of debris ingestion (nutrient dilution) on nutrient gain 2. Model sub-lethal effects of debris ingestion on nutrient intake and growth 3.
Bjorndal, Karen A., Bolten, Alan B.
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

The pursuit of genetic gain in agricultural crops through the application of machine-learning to genomic prediction. [PDF]

Front Genet, 2023
Jones D, Fornarelli R, Derbyshire M, Gibberd M, Barker K, Hane J.   +5 more
europepmc   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Efeito da seleção errônea de machos sobre ganhos genéticos, utilizando-se simulação Effect of errors in the selection of males on the genetic gain using simulation

Revista Brasileira de Zootecnia, 1999
Populações simuladas foram usadas para verificar o efeito de erros na seleção de machos sobre estimativas de ganhos genéticos, ao longo de dez gerações de seleção, usando o BLUP.
Paulo Luiz Souza Carneiro, Ricardo Frederico Euclydes, Martinho de Almeida e Silva, Paulo Sávio Lopes, Robledo de Almeida Torres, Antônio Policarpo Souza Carneiro, Rodolpho de Almeida Torres Filho   +6 more
doaj  

Population improvement via recurrent selection drives genetic gain in upland rice breeding. [PDF]

Heredity (Edinb), 2023
Pereira de Castro A, Breseghello F, Furtini IV, Utumi MM, Pereira JA, Cao TV, Bartholomé J.   +6 more
europepmc   +1 more source