Results 151 to 160 of about 588,080 (302)

Defining Multi-Trait Breeding Objectives and Selection Indexes to Develop More Efficient Breeding Programs for Superfine Wool Sheep

Animals
This study aimed to develop an optimized breeding program for the Alpine Merino sheep superfine strain by defining breeding objectives and establishing a multi-trait selection index. Using phenotypic and genetic (co)variance components of wool and growth
Tingting Guo, Wenhui Li, Chao Yuan, Xijun Wang, Jianbin Liu, Bin Liang   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Inflammatory and apoptotic genetic markers associate with specific Crohn’s disease phenotypes [PDF]

, 2019
Objectives: NIPT continues to expend and offer the most advanced testing option. High coverage sequencing NIPT extended the availability of clinically relevant information.
Zukić, Branka, Stanković, Biljana, Klaassen Ljubičić, Kristel, Nikčević, Gordana, Dragašević, Sanja, Kotur, Nikola, Pavlović, Sonja, Srzentić Dražilov, Sanja, Popović, Dragan   +8 more
core  

Genetic Merit of Parents and Heterosis in Cassava (Manihot esculenta Crantz)

Horticulturae
Cassava breeders are led to discard plants before evaluating families, failing to obtain important information, such as the genetic merit of the parents.
Vanderlei da Silva Santos, Helcio Duarte Pereira, Juraci Souza Sampaio Filho, Luciano Rogério Braatz de Andrade   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Realized genetic gain in rice: achievements from breeding programs [PDF]

Genetic improvement is crucial for ensuring food security globally. Indeed, plant breeding has contributed significantly to increasing the productivity of major crops, including rice, over the last century.
Bartholome, Jérôme, Covarrubias Pazaran, Giovanny Eduardo, Seck, Fallou, Gueye, Tala   +3 more
core  

Observation of Genetic Gain with Instrumental Insemination of Honeybee Queens. [PDF]

Insects, 2023
Maucourt S, Rousseau A, Fortin F, Robert C, Giovenazzo P.   +4 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source