Results 151 to 160 of about 5,638,229 (338)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

The pursuit of genetic gain in agricultural crops through the application of machine-learning to genomic prediction. [PDF]

Front Genet, 2023
Jones D, Fornarelli R, Derbyshire M, Gibberd M, Barker K, Hane J.   +5 more
europepmc   +1 more source

Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q [PDF]

, 1997
Kerstin Heselmeyer, Merryn Macville, Evelin Schröck, Harald Blegen, Ann Hellström, Keerti V. Shah, Gert Auer, Thomas Ried   +7 more
openalex   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Population improvement via recurrent selection drives genetic gain in upland rice breeding. [PDF]

Heredity (Edinb), 2023
Pereira de Castro A, Breseghello F, Furtini IV, Utumi MM, Pereira JA, Cao TV, Bartholomé J.   +6 more
europepmc   +1 more source

Are genetic determinants of weight gain modified by leisure-time physical activity? A prospective study of Finnish twins [PDF]

, 1997
Berit L. Heitmann, Jaakko Kaprio, J. R. Harris, A Rissanen, Maarit Korkeila, M. Koskenvuo   +5 more
openalex   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Simulations of rate of genetic gain in dry bean breeding programs. [PDF]

Theor Appl Genet, 2023
Lin J, Arief V, Jahufer Z, Osorno J, McClean P, Jarquin D, Hoyos-Villegas V.   +6 more
europepmc   +1 more source

Southeastern Conifers: Genetic Gain from Mass Controlled Pollination and Topworking [PDF]

, 1997
David L. Bramlett
openalex   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source