Results 221 to 230 of about 5,638,229 (338)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Genomic selection shows improved expected genetic gain over phenotypic selection of agronomic traits in allotetraploid white clover. [PDF]

Theor Appl Genet
Ehoche OG, Arojju SK, Jahufer MZZ, Jauregui R, Larking AC, Cousins G, Tate JA, Lockhart PJ, Griffiths AG.   +8 more
europepmc   +1 more source

Deterministic and stochastic modelling of impacts from genomic selection and phenomics on genetic gain for perennial ryegrass dry matter yield. [PDF]

Sci Rep, 2021
Jahufer MZZ, Arojju SK, Faville MJ, Ghamkhar K, Luo D, Arief V, Yang WH, Sun M, DeLacy IH, Griffiths AG, Eady C, Clayton W, Stewart AV, George RM, Hoyos-Villegas V, Basford KE, Barrett B.   +16 more
europepmc   +1 more source

Genetic Statistical Analysis on Carcass Traits and Daily Gain of Japanese Black Cattle in Southern Part of Iwate Prefecture

, 2003
Keisuke KAWADA, Shigeto KANEMATSU, Y. Kurosawa, Takayuki Ibi, Yoshiyuki Sasaki   +4 more
openalex   +2 more sources

Application of Random Regression Model to Estimate Genetic Parameters for Average Daily Gains in Lori-Bakhtiari Sheep Breed of Iran [PDF]

, 2007
H Farhangfar, H Naeemipour, B. Zinvand
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Impact of Implementing Female Genomic Selection and the Use of Sex-Selected Semen Technology on Genetic Gain in a Dairy Herd in New Zealand. [PDF]

Int J Mol Sci
Mckimmie C, Forutan M, Tajet HM, Ehsani A, Hickford J, Amirpour H.   +5 more
europepmc   +1 more source

Impact of Genomic Prediction Model, Selection Intensity, and Breeding Strategy on the Long-Term Genetic Gain and Genetic Erosion in Soybean Breeding. [PDF]

Front Genet, 2021
da Silva ÉDB, Xavier A, Faria MV.
europepmc   +1 more source

Estimation of Genetic-Gain Multipliers for Modeling Douglas-Fir Height and Diameter Growth [PDF]

, 2008
Peter Gould, R. Johnson, David D. Marshall, Greg Johnson   +3 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source