FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Assessing genetic gain and diversity in Ethiopian bread wheat across six decades. [PDF]
Sci RepBerta S +4 more
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Understanding rates of genetic gain in sorghum [Sorghum bicolor (L.) Moench] in the United States. [PDF]
Plant GenomeSingh J +6 more
europepmc +1 more source
Maternal genetic contribution to pre-pregnancy obesity, gestational weight gain, and gestational diabetes mellitus [PDF]
, 2019 Selvihan Beysel +6 more
openalex +1 more source
Wheat genetic gains for two distinct management schemes in China: An analysis of elite spring type genotypes [PDF]
, 2020 Mingliang Ding +7 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Multi-Decadal Analysis on the Impact of Climate Change, Genetic Gain, Cultivar Type, and Harvest Timing on Main and Ratoon Rice Yield and Quality. [PDF]
Glob Chang BiolWilson LT, Samonte SOPB, Yang Y.
europepmc +1 more source
Symmetric response to competition in binary mixtures of cultivars associates with genetic gain in wheat yield. [PDF]
Evol Appl, 2021 Cossani CM, Sadras VO.
europepmc +1 more source