Results 211 to 220 of about 1,295,297 (304)

Impact of Implementing Female Genomic Selection and the Use of Sex-Selected Semen Technology on Genetic Gain in a Dairy Herd in New Zealand. [PDF]

Int J Mol Sci
Mckimmie C, Forutan M, Tajet HM, Ehsani A, Hickford J, Amirpour H.   +5 more
europepmc   +1 more source

Deterministic and stochastic modelling of impacts from genomic selection and phenomics on genetic gain for perennial ryegrass dry matter yield. [PDF]

Sci Rep, 2021
Jahufer MZZ, Arojju SK, Faville MJ, Ghamkhar K, Luo D, Arief V, Yang WH, Sun M, DeLacy IH, Griffiths AG, Eady C, Clayton W, Stewart AV, George RM, Hoyos-Villegas V, Basford KE, Barrett B.   +16 more
europepmc   +1 more source

Multi-stage selection for genetic gain [PDF]

Heredity, 1964
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimal Combination of Different Selection and Mating Strategies on Exploiting Genetic Diversity and Genetic Gain in Small Pig Conservation Populations. [PDF]

J Anim Breed Genet
Zhao Q, Liu H, Zhang Q, Qadri QR, Pan Y, Su G, Li P, Huang R.   +7 more
europepmc   +1 more source

Impact of Genomic Prediction Model, Selection Intensity, and Breeding Strategy on the Long-Term Genetic Gain and Genetic Erosion in Soybean Breeding. [PDF]

Front Genet, 2021
da Silva ÉDB, Xavier A, Faria MV.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Optimal implementation of genomic selection in clone breeding programs exemplified in potato: II. Effect of selection strategy and cross-selection method on long-term genetic gain. [PDF]

Plant Genome
Wu PY, Stich B, Hartje S, Muders K, Prigge V, Van Inghelandt D.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The effect of phenotyping, adult selection, and mating strategies on genetic gain and rate of inbreeding in black soldier fly breeding programs. [PDF]

Genet Sel Evol
Slagboom M, Nielsen HM, Kargo M, Henryon M, Hansen LS.   +4 more
europepmc   +1 more source