Results 221 to 230 of about 1,295,297 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic Gain and Inbreeding in Different Simulated Genomic Selection Schemes for Grain Yield and Oil Content in Safflower. [PDF]

Plants (Basel)
Zhao H, Khansefid M, Lin Z, Hayden MJ.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Improving genetic gain in postpartum cows: a modified ovarian superstimulation protocol for ovum pick-up-in vitro embryo production during the voluntary waiting period. [PDF]

J Anim Sci
Xiao J, Tian M, Yuan H, Ren H, Li H, Xie C, Huang C, Wang B, Wang Y, Jin Y, Lin P.   +10 more
europepmc   +1 more source

Genetic gain for rice yield in rainfed environments in India.

Field Crops Res, 2021
Kumar A, Raman A, Yadav S, Verulkar SB, Mandal NP, Singh ON, Swain P, Ram T, Badri J, Dwivedi JL, Das SP, Singh SK, Singh SP, Kumar S, Jain A, Chandrababu R, Robin S, Shashidhar HE, Hittalmani S, Satyanarayana P, Venkateshwarlu C, Ramayya J, Naik S, Nayak S, Dar MH, Hossain SM, Henry A, Piepho HP.   +27 more
europepmc   +1 more source

Strategies Using Genomic Selection to Increase Genetic Gain in Breeding Programs for Wheat. [PDF]

Front Genet, 2020
Tessema BB, Liu H, Sørensen AC, Andersen JR, Jensen J.   +4 more
europepmc   +1 more source

Gaining Ground in the Genetics of Gastric Cancer [PDF]

Gastroenterology, 2017
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic gain in sire selection

, 2018
openaire   +3 more sources