Results 191 to 200 of about 1,295,297 (304)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Multi-Decadal Analysis on the Impact of Climate Change, Genetic Gain, Cultivar Type, and Harvest Timing on Main and Ratoon Rice Yield and Quality. [PDF]

Glob Chang Biol
Wilson LT, Samonte SOPB, Yang Y.
europepmc   +1 more source

Genomic selection and genetic gain for nut yield in an Australian macadamia breeding population. [PDF]

BMC Genomics, 2021
O'Connor KM, Hayes BJ, Hardner CM, Alam M, Henry RJ, Topp BL.   +5 more
europepmc   +1 more source

Soybean: Genetic Gain × Fertilizer Nitrogen Interaction

Kansas Agricultural Experiment Station Research Reports, 2017
O. Ortez, F. Salvagiotti, Eric Adee, J. Enrico, I. A. Ciampitti   +4 more
openaire   +2 more sources

Deciphering the genetics of resistance to weight gain [PDF]

Nature Reviews Endocrinology, 2020
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Realized genetic gain for yield and yield attributes in groundnut breeding at ICRISAT from an ERA trial. [PDF]

Front Plant Sci
Behera PP, Deshmukh D, Vemula AK, Bangaru K, Bagudam R, Mathew A, Purohit A, Vishnumolakala A, Wankhade AP, Kounain S, Guguloth N, Variath MT, Kurva M, Potupureddi G, Muragesan S, Raman A, Pasupuleti J.   +16 more
europepmc   +1 more source

Symmetric response to competition in binary mixtures of cultivars associates with genetic gain in wheat yield. [PDF]

Evol Appl, 2021
Cossani CM, Sadras VO.
europepmc   +1 more source

Heritability and Genetic Gain in Maize

ANBAR JOURNAL OF AGRICULTURAL SCIENCES, 2010
Benan H. Hadi, Karyma M. Wuhaib
openaire   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source