Results 181 to 190 of about 585,798 (302)

Optimal Contribution Selection Improves the Rate of Genetic Gain in Grain Yield and Yield Stability in Spring Canola in Australia and Canada. [PDF]

Plants (Basel), 2023
Cowling WA, Castro-Urrea FA, Stefanova KT, Li L, Banks RG, Saradadevi R, Sass O, Kinghorn BP, Siddique KHM.   +8 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Inter-plot competition in hybrid maize multi-environment yield trials in Ethiopia can reduce rate of genetic gain. [PDF]

Theor Appl Genet
Keno T, Mace E, Godwin I, Jordan D, Kelly A.   +4 more
europepmc   +1 more source

India's rainfed sorghum improvement: Three decades of genetic gain assessment for yield, grain quality, grain mold and shoot fly resistance. [PDF]

Front Plant Sci, 2022
Nagesh Kumar MV, Ramya V, Govindaraj M, Dandapani A, Maheshwaramma S, Ganapathy KN, Kavitha K, Goverdhan M, Jagadeeshwar R.   +8 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Assessing genetic gain and diversity in Ethiopian bread wheat across six decades. [PDF]

Sci Rep
Berta S, Menamo TM, Tadesse Z, Birhan T, Tesfaye Abebe A.   +4 more
europepmc   +1 more source

Maximizing genetic gain through unlocking genetic variation in different ecotypes of kalmegh (Andrographis paniculata (Burm. f.) Nee). [PDF]

Front Plant Sci, 2022
Chaturvedi T, Gupta AK, Shanker K, Dubey BK, Tiwari G.   +4 more
europepmc   +1 more source

Inflammatory and apoptotic genetic markers associate with specific Crohn’s disease phenotypes

, 2019
Objectives: NIPT continues to expend and offer the most advanced testing option. High coverage sequencing NIPT extended the availability of clinically relevant information.
Zukić, Branka, Stanković, Biljana, Klaassen Ljubičić, Kristel, Nikčević, Gordana, Dragašević, Sanja, Kotur, Nikola, Pavlović, Sonja, Srzentić Dražilov, Sanja, Popović, Dragan   +8 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Correction: Optimizing progeny size and number of crosses under genomic selection: insights into additive and epistatic contributions to long‑term genetic gain. [PDF]

Theor Appl Genet
da Silva Viana J, DoVale JC, Fritsche-Neto R.   +2 more
europepmc   +1 more source