Results 171 to 180 of about 53,278 (329)

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Development and Retrospective Application of Novel Outcome Measure: Sturge–Weber Syndrome Acute Crisis (SWAC) Index

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Sturge–Weber syndrome (SWS) symptoms frequently overlap in neurological acute crises (ACs) presenting with seizures, stroke‐like episodes (SLE), and headaches. Recent efforts to develop a prospective drug trial highlighted the need for a new outcome measure capable of quantifying these symptoms during an SWS AC.
Kieran D. McKenney, Luther G. Kalb, Adrienne M. Hammill, Anne M. Comi   +3 more
wiley   +1 more source

Generalized Fast Discharges Along the Genetic Generalized Epilepsy Spectrum: Clinical and Prognostic Significance. [PDF]

Front Neurol, 2022
Cerulli Irelli E, Barone FA, Mari L, Morano A, Orlando B, Salamone EM, Marchi A, Fanella M, Fattouch J, Placidi F, Giallonardo AT, Izzi F, Di Bonaventura C.   +12 more
europepmc   +1 more source

Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders. [PDF]

, 2019
BACKGROUND:Neurodevelopmental disorders (NDDs) such as autism spectrum disorder, intellectual disability, developmental disability, and epilepsy are characterized by abnormal brain development that may affect cognition, learning, behavior, and motor ...
Amini, Hajar, Chow, Julie, Girirajan, Santhosh, Hormozdiari, Farhad, Hormozdiari, Fereydoun, Jensen, Matthew, Penn, Osnat, Shifman, Sagiv   +7 more
core  

Volume changes of medial temporal lobe structures in patients with genetic generalized and temporal lobe epilepsy in relation to neuropsychological functions [PDF]

, 2022
Anna Bochyńska, Grzegorz Witkowski, Magdalena Gugała-Iwaniuk, Danuta Ryglewicz, Halina Sienkiewicz‐Jarosz   +4 more
openalex   +1 more source

Neonatal Seizures in Tuberous Sclerosis Complex: A Case Series

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Epilepsy affects up to 90% of patients with tuberous sclerosis complex (TSC); earlier seizure onset is associated with worse neurocognitive outcomes. The incidence of neonatal seizures in TSC is unknown, although in a recent multicenter trial 23% of infants with TSC were excluded prior to randomization because of pre‐existing ...
Kristina Jülich, Kristen Arredondo
wiley   +1 more source

Genetic Animal Models of Idiopathic Generalized Epilepsies: What Can We Learn from Them?

Biomedicines
The use of animal models of idiopathic generalized epilepsy (IGE) is of great importance in the field of epilepsy research, with IGE affecting more than 20 million people worldwide.
Bernard Lakaye, Laurent Nguyen
doaj   +1 more source

16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy [PDF]

, 2017
Rolandic epilepsy (RE) is the most common idiopathic focal childhood epilepsy. Its molecular basis is largely unknown and a complex genetic etiology is assumed in the majority of affected individuals.
Ameil, Agnès, Andrieux, Joris, Becker, Albert J., Becker, Felicitas, Beckmann, Jacques S., Berkovic, Samuel F., Bouquillon, Sonia, Boute, Odile, Campus, Kiel, Claes, Lieve, Cuisset, Jean Marie, Cuvellier, Jean-Christophe, Dahl, Hans-Henrik M., David, Albert, de Flandre, Jeanne, De Jonghe, Peter, de Kovel, Carolien, de Vries, Bert, Deconinck, Tine, Delrue, Marie-Ange, Deprez, Liesbet, Doco-Fenzy, Martine, Elger, Christian E., Fernandez, Bridget A., Feucht, Martha, Feucht, Martha, Franke, Andre, Gaus, Verena, Geldner, Julia, Geldner, Julia, Gieger, Christian, Gruber-Sedlmayr, Ursula, Gruber-Sedlmayr, Ursula, Haberlandt, Edda, Haberlandt, Edda, Hahn, Andreas, Hamer, Hajo M., Helbig, Ingo, Herms, Stefan, Heron, Delphine, Hildebrand, Michael S., Hjalgrim, Helle, Hoffmann, Per, Jacquemont, Sebastien, Janz, Dieter, Keren, Boris, Kleefuß-Lie, Ailing A., Klein, Karl Martin, Klitten, Laura L., Koeleman, Bobby P.C., Kunz, Wolfram S., Lal, Dennis, Lal, Dennis, Lebel, Robert, Lebon, Sebastien, Leheup, Bruno, Lerche, Holger, Lerche, Holger, Lewis, Suzanne, Lindhout, Dick, Mefford, Heather, Mencarelli, Maria Antonietta, Mignot, Cyril, Minet, Jean-Claude, Moerman, Alexandre, Morice-Picard, Fanny, Mucciolo, Mafalda, Muhle, Hiltrud, Männik, Katrin, Mörzinger, Martina, Møller, Rikke S., Neophytou, Birgit, Neophytou, Birgit, Neubauer, Bernd, Neubauer, Bernd A., Nürnberg, Peter, Nürnberg, Peter, Oertel, Wolfgang H., Ostertag, Philipp, Ounap, Katrin, Pasquier, Laurent, Petit, Florence, Ragona, Francesca, Rajcan-Separovic, Evica, Regan, Brigid M., Reif, Philipp S., Reinthaler, Eva M., Reinthaler, Eva M., Renieri, Alessandra, Reymond, Alexandre, Rieubland, Claudine, Roche, Laurian, Roche, Laurian, Ronen, Gabriel M., Ronen, Gabriel M., Rosenow, Felix, Salengro, Roger, Sander, Thomas, Sander, Thomas, Sanlaville, Damien, Sarrazin, Elisabeth, Scheffer, Ingrid E., Schmitz, Bettina, Schoch, Susanne, Shen, Yiping, Silfhout, Anneke Vulto-van, Smets, Katrien, Steinböck, Hannelore, Steinböck, Hannelore, Stephani, Ulrich, Suls, Arvid, Surges, Rainer, Toliat, Mohammad R., Trucks, Holger, Van Dyck, Tine, van Haelst, Mieke, von Spiczak, Sarah, Waldenberger, Melanie, Weber, Yvonne, Weckhuysen, Sarah, Winterer, Georg, Wittig, Michael, Zimprich, Fritz, Zimprich, Fritz   +123 more
core  

Coexistence of Genetic Generalized Epilepsy and Temporal Lobe Epilepsy

International Journal of Epilepsy, 2023
Kheta Ram Sharma, Naman Agarwal, Smahita Panda, Sarbesh Tiwari   +3 more
openaire   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source