Results 231 to 240 of about 5,764,173 (258)

BridGE: a pathway-based analysis tool for detecting genetic interactions from GWAS. [PDF]

Nat Protoc
Hajiaghabozorgi M, Fischbach M, Albrecht M, Wang W, Myers CL.   +4 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Identifying latent genetic interactions in genome-wide association studies using multiple traits. [PDF]

Genome Med
Bass AJ, Bian S, Wingo AP, Wingo TS, Cutler DJ, Epstein MP.   +5 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Large language model based framework for automated extraction of genetic interactions from unstructured data. [PDF]

PLoS One
Gill JK, Chetty M, Lim S, Hallinan J.
europepmc   +1 more source

Rhizobial genetic elements and the extent of genetic interactions in the field

, 1996
Hirsch, P. R., Mendum, T. A.
core  

Environmental-genetic interactions in ageing and dementia across Latin America. [PDF]

Nat Rev Neurol
Ibanez A, Slachevsky A.
europepmc   +1 more source

Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase. [PDF]

mBio
Ghosh S, Sanchez AM, Schwer B, Prucker I, Jork N, Jessen HJ, Shuman S.   +6 more
europepmc   +1 more source

Genomic insights and advanced machine learning: characterizing autism spectrum disorder biomarkers and genetic interactions. [PDF]

Metab Brain Dis
Nahas LD, Datta A, Alsamman AM, Adly MH, Al-Dewik N, Sekaran K, Sasikumar K, Verma K, Doss GPC, Zayed H.   +9 more
europepmc   +1 more source