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mSphere of Influence: the Power of Yeast Genetics Still Going Strong! [PDF]
Felipe Santiago-Tirado studies the cell biology of cryptococcal infections. In this mSphere of Influence article, he reflects on how the papers “Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans” (https://doi ...
Felipe H. Santiago-Tirado
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Learning Yeast Genetics from Miro Radman [PDF]
Miroslav Radman’s far-sighted ideas have penetrated many aspects of our study of the repair of broken eukaryotic chromosomes. For over 35 years my lab has studied different aspects of the repair of chromosomal breaks in the budding yeast, Saccharomyces ...
James E. Haber
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Development of a rapid reverse genetics system for feline coronavirus based on TAR cloning in yeast
IntroductionReverse genetics has become an indispensable tool to gain insight into the pathogenesis of viruses and the development of vaccines. The yeast-based synthetic genomics platform has demonstrated the novel capabilities to genetically reconstruct
Hongmin Cao +3 more
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Forward Chemical Genetics in Yeast for Discovery of Chemical Probes Targeting Metabolism
The many virtues that made the yeast Saccharomyces cerevisiae a dominant model organism for genetics and molecular biology, are now establishing its role in chemical genetics.
Marie Evangelista +3 more
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My Early Years of Yeast Mitochondrial Genetics
There have been massive technological advances in molecular biology and genetics over the past five decades. I have personally experienced these advances and here I reflect on those origins, from my perspective, studying yeast mitochondrial genetics ...
Ian G. Macreadie
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Power2: The power of yeast genetics applied to the powerhouse of the cell [PDF]
Jared Rutter, Adam Hughes
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Absorbance Spectroscopy of Heads, Hearts and Tails Fractions in Fruit Spirits
There is a large economic interest to characterize heads, hearts and tails fractions during fruit spirit distillation by simple, fast, low-volume and low-cost analytical methods.
Jens Bohn +4 more
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Yeast and Virus-like Particles: A Perfect or Imperfect Couple?
Virus-like particles (VLPs) comprise viral structural proteins that self-assemble to form a particle similar to the native virus capsid. Since their discovery, they have been employed mainly as vaccines to prevent viral infection because they can elicit ...
Sara Brachelente +2 more
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Complex interactions among DNA and nuclear proteins maintain genome organization and stability. The nuclear proteins, particularly the histones, organize, compact, and preserve the stability of DNA, but also allow its dynamic reorganization whenever the ...
Bela Vasileva +4 more
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Microtubules are critical for a variety of cellular processes such as chromosome segregation, intracellular transport and cell shape. Drugs against microtubules have been widely used in cancer chemotherapies, though the acquisition of drug resistance has
Jun Morishita, Paul Nurse
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