Results 11 to 20 of about 845,439 (243)
Identification of a small RhoA GTPase inhibitor effective in fission yeast and human cells
The Rho GTPase family proteins are key regulators of cytoskeletal dynamics. Deregulated activity of Rho GTPases is associated with cancers and neurodegenerative diseases, and their potential as drug targets has long been recognized. Using an economically
Jun Morishita, Paul Nurse
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Technological advances are continuously revealing new genetic variants that are often difficult to interpret. As one of the most genetically tractable model organisms, yeast can have a central role in determining the consequences of human genetic ...
Tiziana Cervelli +3 more
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Impact of particle size reduction on high gravity enzymatic hydrolysis of steam-exploded wheat straw
Article Highlights Fiber size reduction benefits enzymatic high gravity hydrolysis of steam-exploded wheat straw. Small fiber size of ≤ 2.5 mm enables saccharification at 35% w/w solid loadings.
Luis Hoppert, Daniel Einfalt
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Determination of relative volatilities of flavour compounds in hydro-alcoholic solutions is usually performed by time-consuming and costly standard methods such as the Gillespie dynamic recirculation method. This study tested a quick and easy method with
Manami Yagishita +2 more
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Mitogen activated protein kinase (MAPK) signaling pathways execute essential functions in eukaryotic organisms by transducing extracellular stimuli into adaptive cellular responses.
Elisa Gómez-Gil +8 more
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Crossing paths and avoiding catastrophe—an outsider’s inside view of yeast genetics [PDF]
Daniel Hartl, Terrance G Cooper
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Nonconventional yeast species hold the promise to provide novel metabolic routes to produce industrially relevant compounds and tolerate specific stressors, such as cold temperatures.
David Henriques +8 more
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Summary: Non-muscle myosin II activation by regulatory light chain (Rlc1Sp) phosphorylation at Ser35 is crucial for cytokinesis during respiration in the fission yeast Schizosaccharomyces pombe.
Francisco Prieto-Ruiz +6 more
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The Fission Yeast Cell Integrity Pathway: A Functional Hub for Cell Survival upon Stress and Beyond
The survival of eukaryotic organisms during environmental changes is largely dependent on the adaptive responses elicited by signal transduction cascades, including those regulated by the Mitogen-Activated Protein Kinase (MAPK) pathways.
José Cansado +4 more
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Timing of Chromosome DNA Integration throughout the Yeast Cell Cycle
The dynamic mechanism of cell uptake and genomic integration of exogenous linear DNA still has to be completely clarified, especially within each phase of the cell cycle.
Valentina Tosato +3 more
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