Results 161 to 170 of about 294,525 (216)

Genetic Linkage and Hemochromatosis

New England Journal of Medicine, 1979
The two articles on hemochromatosis in this issue, by Beaumont and her colleagues from Rennes, France, and by Cartwright and his associates from Salt Lake City, Utah, show how genetic-linkage studi...
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A study of genetic linkage in schizophrenia

Psychological Medicine, 1987
SynopsisFamilies with more than one member affected by schizophrenia were identified and their members were interviewed. Four standardized diagnostic definitions (PSE, DSM-III, ICD-9, Feighner) were applied to all subjects who were classified as schizophrenic or not schizophrenic according to each definition.
B, Andrew, D C, Watt, C, Gillespie, H, Chapel   +3 more
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A Genetic Linkage Map for the Zebrafish

Science, 1994
To facilitate molecular genetic analysis of vertebrate development, haploid genetics was used to construct a recombination map for the zebrafish Danio ( Brachydanio ) rerio .
John H. Postlethwait, Stephen L. Johnson, Clare N. Midson, William S. Talbot, Michael Gates, Eric W. Ballinger, Dana Africa, Rebecca Andrews, Tim Carl, Judith S. Eisen, Sally Horne, Charles B. Kimmel, Mark Hutchinson, Michele Johnson, Andre Rodriguez   +14 more
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Linkage Analysis of Genetic Disorders

2003
Basic principles and methods of genetic analysis were covered in this chapter. The approaches of linkage analysis for Mendelian or complex disorders can be summarized in the following flowchart (Fig. 2). It is important that the clinical, analytical, and molecular investigators be involved in all steps in the process.
E W, Taylor, J, Xu, E W, Jabs, D A, Meyers   +3 more
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Gene linkage and genetic deafness

International Journal of Pediatric Otorhinolaryngology, 1995
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Cremers, C.W.R.J., Brown, S.D.M., Steel, K.P., Brunner, H.G., Read, A., Kimberling, W.J.   +5 more
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Writings on Genetic Linkage in the Annals

Annals of Human Genetics, 2011
SummaryFrom its inception in 1925 through the almost 30 years that it carried the title of Annals of Eugenics, this journal published numerous articles on the statistical aspects of genetic linkage analysis and its applications to family pedigree data. This overview discusses 40 papers on linkage analysis published in the Annals.
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Bootstrapping in human genetic linkage

Annals of Human Genetics, 1994
SUMMARYLinkage analysis of discrete Mendelian traits has made a major contribution to the mapping of the human genome. However, in more complex situations, particularly Mendelian disorders showing locus heterogeneity, linkage results have sometimes been misleading.
M N, Chiano, J R, Yates
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Genetics and linkage analysis on phosphoglucomutase

Humangenetik, 1971
The current study is based on 454 families with 843 children from two different areas in Western Germany (Marburg and Tfibingen). Only families which have been especially ascertained for these investigations have been taken into account. For the estimation of the gene frequencies 1449 unrelated persons from the areas mentioned above were investigated ...
G G, Wendt, H, Ritter, I, Zilch, G, Tariverdian, G, Utermann, I, Kindermann, G, Kirchberg   +6 more
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Genetic linkage.

British journal of hospital medicine, 1986
Not all doctors would understand the statement "linkage is now established between a DNA marker and the locus for adult polycystic kidney disease at a recombination fraction of 5%". Yet over the next few years increasing numbers of DNA markers linked to single-gene disorders will become available and clinicians will need to identify patients who could ...
J R, Yates, J M, Connor
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Genetic Linkage in Bipolar Disorder

CNS Spectrums, 2003
AbstractBipolar disorder is an etiologically complex syndrome that is dearly heritable. Multiple, genes, working singly or in concert, are likely to cause susceptibility to bipolar disorder. Bipolar disorder genetics has progressed rapidly in the last few decades. However, specific causal genetic mutations for bipolar disorder have not been identified.
Carol A, Mathews, Victor I, Reus
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