Results 251 to 260 of about 3,191,200 (316)

A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA.

Journal of Studies on Alcohol, 1994
Within- and cross-center test-retest studies were conducted to study the reliability of a new, semistructured, comprehensive, polydiagnostic psychiatric interview being used in a multisite genetic linkage study of alcoholism.
K. Bucholz, R. Cadoret, C. Robert Cloninger, S. Dinwiddie, V. Hesselbrock, J. Nurnberger, T. Reich, I. Schmidt, M. Schuckit   +8 more
semanticscholar   +1 more source

Optimizing parental selection for genetic linkage maps.

Genome, 1993
Genetic linkage maps based on restriction fragment length polymorphisms are useful for many purposes; however, different populations are required to fulfill different objectives.
J. Anderson, G. Churchill, J. E. Autrique, S. Tanksley, M. Sorrells   +4 more
semanticscholar   +1 more source

Genetic Linkage and Hemochromatosis

New England Journal of Medicine, 1979
The two articles on hemochromatosis in this issue, by Beaumont and her colleagues from Rennes, France, and by Cartwright and his associates from Salt Lake City, Utah, show how genetic-linkage studi...
openaire   +3 more sources

Construction of integrated genetic linkage maps by means of a new computer package: JOINMAP.

, 1993
Summary A computerized procedure to construct integrated genetic maps is presented. The computer program (Join Map) can handle raw data from F2s, backcrosses and recombinant inbred lines, as well as listed pair-wise recombination frequencies.
P. Stam
semanticscholar   +1 more source

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

Science, 1987
The amyloid beta protein has been identified as an important component of both cerebrovascular amyloid and amyloid plaques of Alzheimer's disease and Down syndrome.
R. Tanzi, J. Gusella, P. Watkins, G. Bruns, P. George-Hyslop, M. Keuren, D. Patterson, S. Pagan, D. Kurnit, R. Neve   +9 more
semanticscholar   +1 more source

Writings on Genetic Linkage in the Annals

Annals of Human Genetics, 2011
SummaryFrom its inception in 1925 through the almost 30 years that it carried the title of Annals of Eugenics, this journal published numerous articles on the statistical aspects of genetic linkage analysis and its applications to family pedigree data. This overview discusses 40 papers on linkage analysis published in the Annals.
Jurg Ott, Jurg Ott
openaire   +3 more sources

PopLDdecay: a fast and effective tool for linkage disequilibrium decay analysis based on variant call format files

Bioinform., 2018
MOTIVATION Linkage disequilibrium (LD) decay is of great interest in population genetic studies. However, no tool is available now to do LD decay analysis from variant call format (VCF) files directly. In addition, generation of pair-wise LD measurements
Chi Zhang, Shanshan Dong, Jun-Yang Xu, Wei-Ming He, Tie-Lin Yang   +4 more
semanticscholar   +1 more source

A study of genetic linkage in schizophrenia

Psychological Medicine, 1987
SynopsisFamilies with more than one member affected by schizophrenia were identified and their members were interviewed. Four standardized diagnostic definitions (PSE, DSM-III, ICD-9, Feighner) were applied to all subjects who were classified as schizophrenic or not schizophrenic according to each definition.
C. Gillespie, David C. Watt, B. Andrew, H. Chapel   +3 more
openaire   +3 more sources

Bootstrapping in human genetic linkage

Annals of Human Genetics, 1994
SUMMARYLinkage analysis of discrete Mendelian traits has made a major contribution to the mapping of the human genome. However, in more complex situations, particularly Mendelian disorders showing locus heterogeneity, linkage results have sometimes been misleading.
J. R. W. Yates, M. N. Chiano
openaire   +3 more sources

A Genetic Linkage Map for the Zebrafish

Science, 1994
To facilitate molecular genetic analysis of vertebrate development, haploid genetics was used to construct a recombination map for the zebrafish Danio ( Brachydanio ) rerio .
Clare N. Midson, Andre Rodriguez, Mark Hutchinson, Sally Horne, John H. Postlethwait, Charles B. Kimmel, Judith S. Eisen, Rebecca Andrews, Dana Africa, Michele Johnson, Tim Carl, Eric W. Ballinger, Michael A. Gates, Stephen L. Johnson, William S. Talbot   +14 more
openaire   +3 more sources