Results 31 to 40 of about 3,634,544 (343)

Quantitative trait loci influencing low density lipoprotein particle size in African Americans

Journal of Lipid Research, 2006
Genomic regions that influence LDL particle size in African Americans are not known. We performed family-based linkage analyses to identify genomic regions that influence LDL particle size and also exert pleiotropic effects on two closely related lipid ...
Iftikhar J. Kullo, Keyue Ding, Eric Boerwinkle, Stephen T. Turner, Mariza de Andrade   +4 more
doaj   +1 more source

Genetics of autistic disorders : review and clinical implications [PDF]

, 2009
Twin and family studies in autistic disorders (AD) have elucidated a high heritability of AD. In this literature review, we will present an overview on molecular genetic studies in AD and highlight the most recent findings of an increased rate of copy ...
Duketis, Eftichia, Freitag, Christine M., Klauck, Sabine M., Staal, Wouter, Waltes, Regina   +4 more
core   +4 more sources

New technologies for delineating and characterizing the lipid exome: prospects for understanding familial combined hyperlipidemia

Journal of Lipid Research, 2009
This review summarizes the progress made in cutting through the biological and genetic complexity of the Gordian knot that is familial combined hyperlipidemia. We particularly focus on how the application of new genomic technologies, especially massively
Stuart D. Horswell, Helen E. Ringham, Carol C. Shoulders   +2 more
doaj   +1 more source

Genomic Resource Development for Hydrangea (Hydrangea macrophylla (Thunb.) Ser.)—A Transcriptome Assembly and a High-Density Genetic Linkage Map

Horticulturae, 2021
Hydrangea (Hydrangea macrophylla) is an important ornamental crop that has been cultivated for more than 300 years. Despite the economic importance, genetic studies for hydrangea have been limited by the lack of genetic resources.
Xingbo Wu, Amanda M. Hulse-Kemp, Phillip A. Wadl, Zach Smith, Keithanne Mockaitis, Margaret E. Staton, Timothy A. Rinehart, Lisa W. Alexander   +7 more
doaj   +1 more source

Construction of an integrated consensus map of the Apple genome based on four mapping populations [PDF]

, 2008
An integrated consensus genetic map for apple was constructed on the basis of segregation data from four genetically connected crosses (C1¿=¿Discovery × TN10-8, C2¿=¿Fiesta × Discovery, C3¿=¿Discovery × Prima, C4¿=¿Durello di Forli × Fiesta) with a total
Dunemann, F., Durel, C.E., Gennari, F., Kodde, L.P., Koller, B., N'Diaye, A., Tartarini, S., Thiermann, M., Weg, W.E., van de   +8 more
core   +3 more sources

A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

Molecular Genetics & Genomic Medicine, 2014
Primary vesicoureteric reflux (VUR), the retrograde flow of urine from the bladder toward the kidneys, results from a developmental anomaly of the vesicoureteric valve mechanism, and is often associated with other urinary tract anomalies.
J. M. Darlow, M. G. Dobson, R. Darlay, C. M. Molony, M. Hunziker, A. J. Green, H. J. Cordell, P. Puri, D. E. Barton   +8 more
doaj   +1 more source

Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers

BMC Genomics, 2012
Background Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS) through the identification of Quantitative Trait Loci and selection of allelic variants of interest in ...
de Miguel Marina, de Maria Nuria, Guevara M, Diaz Luis, Sáez-Laguna Enrique, Sánchez-Gómez David, Chancerel Emilie, Aranda Ismael, Collada Carmen, Plomion Christophe, Cabezas José-Antonio, Cervera María-Teresa   +11 more
doaj   +1 more source

Short communication: Characterization of the genome-wide linkage disequilibrium in 2 divergent selection lines of dairy cows [PDF]

, 2010
The objective of this study was to describe results of a genome-wide map of single nucleotide polymorphisms (SNP) and assess the linkage disequilibrium (LD) level in 2 divergent selection lines of dairy cows. DNA extracted from 299 Holstein cows was used
Banos, G., Coffey, M. P.
core   +1 more source

Functional mapping and annotation of genetic associations with FUMA

Nature Communications, 2017
A main challenge in genome-wide association studies (GWAS) is to pinpoint possible causal variants. Results from GWAS typically do not directly translate into causal variants because the majority of hits are in non-coding or intergenic regions, and the ...
Kyoko Watanabe, E. Taskesen, Arjen van Bochoven, D. Posthuma   +3 more
semanticscholar   +1 more source

High-density SNP genetic linkage map construction and quantitative trait locus mapping for resistance to cucumber mosaic virus in tobacco (Nicotiana tabacum L.)

Crop Journal, 2019
Genetic linkage maps are essential for studies of genetics, genomic structure, and genomic evolution, and for mapping quantitative trait loci (QTL).
Lirui Cheng, Xiaocui Chen, Caihong Jiang, Bing Ma, Min Ren, Yazeng Cheng, Dan Liu, Ruimei Geng, Aiguo Yang   +8 more
doaj   +1 more source