Results 41 to 50 of about 3,184,484 (374)
Coalescence, genetic diversity in sexual populations under selection [PDF]
Proc Natl Acad Sci U S A. Sep 24, 2013; 110: 15836--15841, 2013 In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting interference between linked alleles reduces the efficiency of selection and distorts patterns of genetic diversity ...
arxiv +1 more source
Genetic linkage and natural selection [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2010 The prevalence of recombination in eukaryotes poses one of the most puzzling questions in biology. The most compelling general explanation is that recombination facilitates selection by breaking down the negative associations generated by random drift (i.e. Hill–Robertson interference, HRI). I classify the effects of HRI owing to: deleterious mutation,
openaire +3 more sources
Bioinform., 2003 SUMMARY A website for performing power calculations for the design of linkage and association genetic mapping studies of complex traits. AVAILABILITY The package is made available athttp://statgen.iop.kcl.ac.uk/gpc/.
S. Purcell, S. Cherny, P. Sham
semanticscholar +1 more source
The effect of linkage on establishment and survival of locally beneficial mutations [PDF]
Genetics 197, 317-336 (2014), 2013 When organisms adapt to spatially heterogeneous environments, selection may drive divergence at multiple genes. If populations under divergent selection also exchange migrants, we expect genetic differentiation to be high at selected loci, relative to the baseline caused by migration and genetic drift.
arxiv +1 more source
BMC Genomics, 2012 Background Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS) through the identification of Quantitative Trait Loci and selection of allelic variants of interest in ...
de Miguel Marina +11 more
doaj +1 more source
GENETIC SUBSTANTIATION OF DETERMINATION OF SEX. CONCEPT ABOUT SEX-LINKED INHERITANCE
Вісник проблем біології і медицини, 2019 Material of the article is devoted to the study and understanding of issues associated with the phenomena of heredity. Normal processes of functioning and distribution of genetic material at the chromosomal level of its organization contribute to the ...
Perederii N. A.
doaj +1 more source
Bioinform., 2012 Summary: GenAlEx: Genetic Analysis in Excel is a cross-platform package for population genetic analyses that runs within Microsoft Excel. GenAlEx offers analysis of diploid codominant, haploid and binary genetic loci and DNA sequences.
R. Peakall, P. Smouse
semanticscholar +1 more source
Molecular Genetics & Genomic Medicine, 2014 Primary vesicoureteric reflux (VUR), the retrograde flow of urine from the bladder toward the kidneys, results from a developmental anomaly of the vesicoureteric valve mechanism, and is often associated with other urinary tract anomalies.
J. M. Darlow +8 more
doaj +1 more source
MapChart: software for the graphical presentation of linkage maps and QTLs.
Journal of Heredity, 2002 Over the last 15 years a wealth of linkage maps and quantitative trait loci (QTL) mapping results have become available. The pace of generating this genetic information is accelerating owing to advances in molecular marker technology and the development ...
R. Voorrips
semanticscholar +1 more source
PLoS ONE, 2014 The reliability of genome analysis and proficiency of genetic manipulation requires knowledge of the correspondence between the genetic and cytogenetic maps.
Liying Feng +9 more
doaj +1 more source