Results 41 to 50 of about 3,543,690 (289)

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.

American Journal of Human Genetics, 1998
The contribution of BRCA1 and BRCA2 to inherited breast cancer was assessed by linkage and mutation analysis in 237 families, each with at least four cases of breast cancer, collected by the Breast Cancer Linkage Consortium.
D. Ford, D. Easton, Michael R. Stratton, S. Narod, D. Goldgar, P. Devilee, D. Bishop, B. Weber, G. Lenoir, J. Chang-Claude, H. Sobol, M. Teare, J. Struewing, A. Arason, S. Scherneck, J. Peto, T. Rebbeck, P. Tonin, S. Neuhausen, R. Barkardottir, J. Eyfjord, H. Lynch, B. Ponder, S. Gayther, J. Birch, A. Lindblom, D. Stoppa-Lyonnet, Y. Bignon, Å. Borg, U. Hamann, N. Haites, Rodney J. Scott, C. Maugard, H. Vasen, S. Seitz, L. Cannon-Albright, A. Schofield, M. Zelada-Hedman   +37 more
semanticscholar   +1 more source

Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers

BMC Genomics, 2012
Background Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS) through the identification of Quantitative Trait Loci and selection of allelic variants of interest in ...
de Miguel Marina, de Maria Nuria, Guevara M, Diaz Luis, Sáez-Laguna Enrique, Sánchez-Gómez David, Chancerel Emilie, Aranda Ismael, Collada Carmen, Plomion Christophe, Cabezas José-Antonio, Cervera María-Teresa   +11 more
doaj   +1 more source

Construction of an integrated consensus map of the Apple genome based on four mapping populations [PDF]

, 2008
An integrated consensus genetic map for apple was constructed on the basis of segregation data from four genetically connected crosses (C1¿=¿Discovery × TN10-8, C2¿=¿Fiesta × Discovery, C3¿=¿Discovery × Prima, C4¿=¿Durello di Forli × Fiesta) with a total
Dunemann, F., Durel, C.E., Gennari, F., Kodde, L.P., Koller, B., N'Diaye, A., Tartarini, S., Thiermann, M., Weg, W.E., van de   +8 more
core   +3 more sources

A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

Molecular Genetics & Genomic Medicine, 2014
Primary vesicoureteric reflux (VUR), the retrograde flow of urine from the bladder toward the kidneys, results from a developmental anomaly of the vesicoureteric valve mechanism, and is often associated with other urinary tract anomalies.
J. M. Darlow, M. G. Dobson, R. Darlay, C. M. Molony, M. Hunziker, A. J. Green, H. J. Cordell, P. Puri, D. E. Barton   +8 more
doaj   +1 more source

Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder. [PDF]

, 2014
BackgroundAutism spectrum disorders (ASDs) are male-biased and genetically heterogeneous. While sequencing of sporadic cases has identified de novo risk variants, the heritable genetic contribution and mechanisms driving the male bias are less understood.
Cantor, Rita M, Geschwind, Daniel H, Lowe, Jennifer K, Luo, Rui, Werling, Donna M, Werling, Donna M   +5 more
core   +2 more sources

High-density SNP genetic linkage map construction and quantitative trait locus mapping for resistance to cucumber mosaic virus in tobacco (Nicotiana tabacum L.)

Crop Journal, 2019
Genetic linkage maps are essential for studies of genetics, genomic structure, and genomic evolution, and for mapping quantitative trait loci (QTL).
Lirui Cheng, Xiaocui Chen, Caihong Jiang, Bing Ma, Min Ren, Yazeng Cheng, Dan Liu, Ruimei Geng, Aiguo Yang   +8 more
doaj   +1 more source

Genetics of autistic disorders : review and clinical implications [PDF]

, 2009
Twin and family studies in autistic disorders (AD) have elucidated a high heritability of AD. In this literature review, we will present an overview on molecular genetic studies in AD and highlight the most recent findings of an increased rate of copy ...
Duketis, Eftichia, Freitag, Christine M., Klauck, Sabine M., Staal, Wouter, Waltes, Regina   +4 more
core   +4 more sources

An integrated genetic and cytogenetic map for Zhikong scallop, Chlamys farreri, based on microsatellite markers.

PLoS ONE, 2014
The reliability of genome analysis and proficiency of genetic manipulation requires knowledge of the correspondence between the genetic and cytogenetic maps.
Liying Feng, Liping Hu, Xiaoteng Fu, Huan Liao, Xuan Li, Aibin Zhan, Lingling Zhang, Shi Wang, Xiaoting Huang, Zhenmin Bao   +9 more
doaj   +1 more source

Construction of a high-resolution genetic linkage map and comparative genome analysis for the reef-building coral Acropora millepora [PDF]

, 2009
Section of Integrative Biology, School of Biological Sciences, University of Texas at Austin, 1 University Station C0930, Austin, TX 78712, USABackground: Worldwide, coral reefs are in decline due to a range of anthropogenic disturbances, and are now ...
Matz, Mikhail V., Meyer, Eli, Wang, Shi, Zhang, Lingling   +3 more
core   +2 more sources

Joint assembly and genetic mapping of the Atlantic horseshoe crab genome reveals ancient whole genome duplication [PDF]

, 2013
Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral arthropod traits, and are ...
Brockmann, H Jane, Havlak, Paul, Lv, Jie, Nossa, Carlos, Putnam, Nicholas H, Vincent, Kim, Yue, Jia-Xing   +6 more
core   +2 more sources