Results 41 to 50 of about 283,128 (311)
Construction of High-Density Linkage Maps of Populus deltoides × P. simonii Using Restriction-Site Associated DNA Sequencing. [PDF]
PLoS ONE, 2016 Although numerous linkage maps have been constructed in the genus Populus, they are typically sparse and thus have limited applications due to low throughput of traditional molecular markers. Restriction-site associated DNA sequencing (RADSeq) technology
Chunfa Tong +11 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Skewed RAPD markers in linkage maps of Citrus
Genetics and Molecular Biology, 2004 The objective of this work was to analyze the effects of RAPD markers with skewed segregation on genetic linkage maps. Segregation data for 123 Citrus sinensis (L.) Osbeck cv. Pêra markers and 53 C. reticulata Blanco cv.
Roberto Pedroso de Oliveira +3 more
doaj +1 more source
BMC Genomics, 2021 Background The Chinese giant salamander Andrias davidianus is an important amphibian species in China because of its increasing economic value, protection status and special evolutionary position from aquatic to terrestrial animal.
Qiaomu Hu +6 more
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FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
BMC Genomics, 2017 Background Atlantic cod (Gadus morhua), is known to vary genetically across the North Atlantic, Greenland, and Newfoundland. This genetic variation occurs both spatially and temporally through decades of heavy fishing, and is concentrated in three ...
Bryan T. Barney +3 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
BMC Genetics, 2006 Background A genetic model about quantitative trait loci (QTL) provides a basis to interpret the genetic basis of quantitative traits in a study population, such as additive, dominance and epistatic effects of QTL and the partition of genetic variance ...
Wang Tao, Zeng Zhao-Bang
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Accounting for a quantitative trait locus for plasma triglyceride levels: utilization of variants in multiple genes. [PDF]
PLoS ONE, 2012 For decades, research efforts have tried to uncover the underlying genetic basis of human susceptibility to a variety of diseases. Linkage studies have resulted in highly replicated findings and helped identify quantitative trait loci (QTL) for many ...
Lisa J Martin +2 more
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Genetic linkage analysis [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 IIIStatistical properties of the method of lod scores III1. The test procedure III1.1. Impact of non-sequentiality III1.2. Maximization of the lod score over the [0, 1/2] interval III1.3 References III-2. Genotype information III-2.1. Ambiguity in phenotype-genotype relationships at the disease locus III-2.2.
openaire +3 more sources