Results 61 to 70 of about 3,191,200 (316)
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
Genetic Epidemiology, 2013 Genome‐wide association studies, which typically report regression coefficients summarizing the associations of many genetic variants with various traits, are potentially a powerful source of data for Mendelian randomization investigations.
S. Burgess, A. Butterworth, S. Thompson
semanticscholar +1 more source
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
Investigating chromosomal structural variations in Musa acuminate using NGS approaches : [W077] [PDF]
, 2014 Structural heterozygosity is thought to be one of the main causes of sterility in banana (Musa spp.) hybrids. These structural variations impact chromosomal segregation and recombination, limiting crossing possibilities and complicating genetic analyses.
Baurens, Franc-Christophe +7 more
core
Integrating the markers Pan I and haemoglobin with the genetic linkage map of Atlantic cod (Gadus morhua) [PDF]
, 2010 Background Haemoglobin (Hb) and pantophysin (Pan I) markers have been used intensively in population studies of Atlantic cod (Gadus morhua) and in the analysis of traits such as temperature tolerance, growth characteristics and sexual maturation. We used
Borza, Tudor +3 more
core +3 more sources
, 2013 This study reports a high density genetic linkage map based on the ‘Maryland 96-5722’ by ‘Spencer’ recombinant inbred line (RIL) population of soybean [Glycine max (L.) Merr.] and constructed exclusively with single nucleotide polymorphism (SNP) markers.
M. Akond +10 more
semanticscholar +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
PLoS ONE, 2012 The genetic differences between mungbean and its presumed wild ancestor were analyzed for domestication related traits by QTL mapping. A genetic linkage map of mungbean was constructed using 430 SSR and EST-SSR markers from mungbean and its related ...
T. Isemura +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Learning Expressive Linkage Rules using Genetic Programming [PDF]
Proceedings of the VLDB Endowment (PVLDB), Vol. 5, No. 11, pp.
1638-1649 (2012), 2012 A central problem in data integration and data cleansing is to find entities in different data sources that describe the same real-world object. Many existing methods for identifying such entities rely on explicit linkage rules which specify the conditions that entities must fulfill in order to be considered to describe the same real-world object.
arxiv
Genome-Wide Association and Linkage Analysis of Quantitative Traits: Comparison pf Likelihood-Ratio Test and Conditional Score Statistic [PDF]
, 2009 Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a specific phenotype.
Dupuis, Josée +2 more
core +1 more source