Results 191 to 200 of about 571,568 (315)

Genetic map of the carotid body stem cell niche with focus on the O₂-sensing chemoreceptor cell lineage. [PDF]

Sci Rep
Santamaría-Santiago A, Sobrino V, Luna-Ramírez L, López-Barneo J, Pardal R.   +4 more
europepmc   +1 more source

Construction of a high-resolution genetic map and identification of single nucleotide polymorphism markers relevant to flower stalk height in onion. [PDF]

Front Plant Sci, 2023
Li Y, Huo Y, Yang Y, Wang Z, Sun Y, Liu B, Wu X.   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Construction of high-density bin genetic map and QTL mapping of fruit aroma in longan (<i>Dimocarpus longan</i> Lour.). [PDF]

Front Plant Sci
Hu W, Zhang Q, Deng C, Xu Q, Jiang J, Chen X, Li J, Zhang J, Zheng S.   +8 more
europepmc   +1 more source

Genetic map of regional sulcal morphology in the human brain from UK biobank data. [PDF]

Nat Commun, 2022
Sun BB, Loomis SJ, Pizzagalli F, Shatokhina N, Painter JN, Foley CN, Biogen Biobank Team, Jensen ME, McLaren DG, Chintapalli SS, Zhu AH, Dixon D, Islam T, Ba Gari I, Runz H, Medland SE, Thompson PM, Jahanshad N, Whelan CD.   +18 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Analysis of Autosomal STRs Draws the Current Genetic Map and Evolutionary History of Northernmost South America. [PDF]

Genes (Basel)
Moncada Madero J, Mogollón Olivares F, Suárez Medellín D, Coronel Guzmán A, Casas-Vargas A, Usaquén Martínez W.   +5 more
europepmc   +1 more source

Consensus genetic map and QTLs for morphological and agronomical traits in mungbean using DArT markers. [PDF]

Physiol Mol Biol Plants, 2022
Vu TTH, Kilian A, Carling J, Lawn RJ.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Quantitative Trait Locus Mapping and Candidate Gene Identification for Fruit Acidity in Chinese Dwarf Cherry (<i>Cerasus humilis</i>) Using a High-Density Genetic Map. [PDF]

Genes (Basel)
Guo C, Hu F, Li Y.
europepmc   +1 more source