Results 201 to 210 of about 571,568 (315)

Development of a High-Density Genetic Map for Muscadine Grape Using a Mapping Population from Selfing of the Perfect-Flowered Vine 'Dixie'. [PDF]

Plants (Basel), 2022
Lytkin K, Nosulchak V, Agakhanov M, Matveikina E, Lushchay E, Karzhaev D, Raines E, Vasylyk I, Rybachenko N, Grigoreva E, Volkov V, Volynkin V, Gentzbittel L, Potokina E.   +13 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

High-density genetic map construction using whole-genome resequencing of the <i>Cymbidium eburneum</i>('Duzhan Chun') × <i>Cymbidium insigne</i> ('Meihua Lan') F1 population and localization of flower color genes. [PDF]

Front Plant Sci
Han Y, Cui Y, Chen Y, Rao D, Wu E, Gan R, Li T, Tian M.   +7 more
europepmc   +1 more source

Mapping of Two Major QTLs Controlling Flowering Time in Brassica napus Using a High-Density Genetic Map. [PDF]

Plants (Basel), 2022
Chen L, Lei W, He W, Wang Y, Tian J, Gong J, Hao B, Cheng X, Shu Y, Fan Z.   +9 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Comparative genetic mapping and a consensus interspecific genetic map reveal strong synteny and collinearity within the Citrus genus. [PDF]

Front Plant Sci
Ollitrault P, Hufnagel B, Curk F, Perdereau A, Mournet P, Miranda M, Costantino G, Froelicher Y, Alves M, Forner Giner MA, Smith MW, Aleza P, Luro F, Wulff NA, Peña L, Morillon R, Lemainque A.   +16 more
europepmc   +1 more source

Construction of the first high-density SNP genetic map and identification of QTLs for the natural rubber content in Taraxacum kok-saghyz Rodin. [PDF]

BMC Genomics, 2023
Yang Y, Qin B, Chen Q, Nie Q, Zhang J, Zhang L, Liu S.   +6 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

QTL analysis of sorghum grain traits based on high-density genetic map. [PDF]

J Appl Genet
Cao N, Ding Y, Xu J, Cheng B, Gao X, Li W, Zou G, Zhang L.   +7 more
europepmc   +1 more source

Erratum: A high-density genetic map and QTL fine mapping for growth- and sex-related traits in red swamp crayfish (Procambarus clarkii). [PDF]

Front Genet, 2022
Guo XF, Zhou YL, Liu M, Li Z, Zhou L, Wang ZW, Gui JF.   +6 more
europepmc   +1 more source