Results 201 to 210 of about 4,786,280 (310)

Comparative genetic mapping and a consensus interspecific genetic map reveal strong synteny and collinearity within the Citrus genus. [PDF]

Front Plant Sci
Ollitrault P, Hufnagel B, Curk F, Perdereau A, Mournet P, Miranda M, Costantino G, Froelicher Y, Alves M, Forner Giner MA, Smith MW, Aleza P, Luro F, Wulff NA, Peña L, Morillon R, Lemainque A.   +16 more
europepmc   +1 more source

Mapping of Two Major QTLs Controlling Flowering Time in Brassica napus Using a High-Density Genetic Map. [PDF]

Plants (Basel), 2022
Chen L, Lei W, He W, Wang Y, Tian J, Gong J, Hao B, Cheng X, Shu Y, Fan Z.   +9 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

QTL analysis of sorghum grain traits based on high-density genetic map. [PDF]

J Appl Genet
Cao N, Ding Y, Xu J, Cheng B, Gao X, Li W, Zou G, Zhang L.   +7 more
europepmc   +1 more source

Development of a High-Density Genetic Map for Muscadine Grape Using a Mapping Population from Selfing of the Perfect-Flowered Vine 'Dixie'. [PDF]

Plants (Basel), 2022
Lytkin K, Nosulchak V, Agakhanov M, Matveikina E, Lushchay E, Karzhaev D, Raines E, Vasylyk I, Rybachenko N, Grigoreva E, Volkov V, Volynkin V, Gentzbittel L, Potokina E.   +13 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

High-density genetic map construction using whole-genome resequencing of the <i>Cymbidium eburneum</i>('Duzhan Chun') × <i>Cymbidium insigne</i> ('Meihua Lan') F1 population and localization of flower color genes. [PDF]

Front Plant Sci
Han Y, Cui Y, Chen Y, Rao D, Wu E, Gan R, Li T, Tian M.   +7 more
europepmc   +1 more source

Construction of the first high-density SNP genetic map and identification of QTLs for the natural rubber content in Taraxacum kok-saghyz Rodin. [PDF]

BMC Genomics, 2023
Yang Y, Qin B, Chen Q, Nie Q, Zhang J, Zhang L, Liu S.   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

High-density genetic map construction and QTL analysis of the first flower node in kenaf using RAD-seq. [PDF]

BMC Plant Biol
Li H, Chen A, Tang H, Luan M.
europepmc   +1 more source