Results 101 to 110 of about 5,022,316 (352)

Genetic diversity of tropical-adapted onion germplasm assessed by RAPD markers [PDF]

open access: diamond, 2012
Maria do Desterro Mendes dos Santos   +6 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Análisis de la variabilidad genética de la colección colombiana de musáceas usando marcadores isoenzimáticos Analysis of the genetic variability of colombian collection of Musaceae using isozyme markers

open access: yesActa Agronómica, 2011
La Colección Colombiana de Musáceas (CCM) es la única a nivel mundial que representa un alto valor por ser la que posee introducciones andinas de altura (> 1500 m.s.n.m.).
Martha C Giraldo   +3 more
doaj  

Genotyping by Amplicon Sequencing (GBAS) With Newly Developed SSR and EPIC Markers Reveals Structure in Populations of the Green Toad (Bufotes viridis) Across Rural and Urban Environments

open access: yesEcology and Evolution
Microsatellites (SSRs) are reliable markers for population genetic analyses but often suffer from null alleles caused by mutations in primer binding sites.
Vincent Kendlbacher   +7 more
doaj   +1 more source

Evaluation of the Genetic Diversity of Greek Garlic (Allium sativum L.) Accessions Using DNA Markers and Association with Phenotypic and Chemical Variation [PDF]

open access: gold, 2023
Charikleia Papaioannou   +5 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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