Results 81 to 90 of about 3,863,878 (307)

Genomics and animal production

Revista Peruana de Biología, 2020
Developing countries have the challenge of achieving food security in a world context that is affected by climate change and global population growth. Molecular Genetics and genomics are proposed as technologies that will help to achieve sustainable food
F. Abel Ponce de León, Gustavo A. Gutierrez   +1 more
doaj   +1 more source

Genetic Markers as Instrumental Variables [PDF]

The use of genetic markers as instrumental variables (IV) is receiving increasing attention from epidemiologists, economists, statisticians and social scientists.
Frank Windmeijer, Carol Propper, Stephanie von Hinke Kessler Scholder, George Davey Smith, Debbie A. Lawlor   +4 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cholinergic Pathway SNPs and Postural Control in 477 Older Adults

Frontiers in Aging Neuroscience, 2018
Objective: To determine whether single nucleotide polymorphisms (SNPs) of the cholinergic system and quantitative parameters of postural control are associated in healthy older adults.
Carina Arnold, Carina Arnold, Claudia Schulte, Claudia Schulte, Mariana Moscovich, Ulrike Sünkel, Ulrike Sünkel, Laura Zaunbrecher, Laura Zaunbrecher, Florian Metzger, Florian Metzger, Thomas Gasser, Thomas Gasser, Gerhard W. Eschweiler, Gerhard W. Eschweiler, Ann-Kathrin Hauser, Ann-Kathrin Hauser, Daniela Berg, Daniela Berg, Daniela Berg, Walter Maetzler, Walter Maetzler, Walter Maetzler   +22 more
doaj   +1 more source

Development of a high-throughput microsatellite typing approach for forensic and population genetic analysis of wild and domestic African Bovini [PDF]

, 2008
Conservation management and forensic traceability of African buffalo and cattle rely on the timely provision of unbiased and accurate genetic information.
Plessis, S., du, Kryger, P., Greyling, B.J., Hooft, W.F., van, Helden, P., van, Getz, W.M., Bastos, A.D.S.   +6 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Human complex mixture analysis by “FD Multi-SNP Mixture Kit”

Frontiers in Genetics
IntroductionMultiple linked single nucleotide polymorphisms (SNPs) have shown potential in personal identification and mixture detection. However, the limited number of marker and sequencing errors have obstructed accurate DNA typing.MethodsTo develop ...
Anqi Chen, Lun Li, Lun Li, Junfei Zhou, Junfei Zhou, Tiantian Li, Tiantian Li, Chunyan Yuan, Hai Peng, Hai Peng, Chengtao Li, Chengtao Li, Suhua Zhang, Suhua Zhang   +13 more
doaj   +1 more source

Covariation between intraspecific genetic diversity and species diversity within a plant functional group [PDF]

, 2008
1. Species diversity and genetic diversity are fundamental components of biodiversity. A primary goal of biodiversity studies is to explain the distribution of species and alleles in space and time.
Enright, N.J., Krauss, S., He, Tianhua, Enright, Neal, Lamont, B.B., He, T., Krauss, S.L., Lamont, Byron, Miller, B.P., Miller, Ben   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source