Results 71 to 80 of about 3,863,878 (307)

Genetic Markers [PDF]

Circulation, 2004
The recent completion of the Human Genome Project has provided an unprecedented opportunity for researchers to identify high-risk patients and improve human health through the use of technologies that integrate the entire genome. In the past, disorders that yielded their secrets to genetic investigations tended to be rare, single-gene conditions (eg ...
Gary H, Gibbons, Choong Chin, Liew, Mark O, Goodarzi, Jerome I, Rotter, Willa A, Hsueh, Helmy M, Siragy, Richard, Pratt, Victor J, Dzau   +7 more
openaire   +2 more sources

Estimation of pedigree errors in the UK dairy population using microsatellite markers and the impact on selection [PDF]

, 2002
The proportion of cows in the UK dairy herd whose sires were misidentified was estimated using DNA markers. Genetic marker genotypes were determined on 568 cows (from 168 milk samples and 400 hair samples) and 96 putative sires (from semen samples).
Visscher, PM, Woolliams, JA, Visscher, Peter, Williams, J.L., Smith, D, Woolliams, John, Williams, JL, Smith, D., D. Smith, J.A. Woolliams, J.L. Williams, P.M. Visscher   +11 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Searching for the Transcriptomic Signature of Immune Tolerance Induction—Biomarkers of Safety and Functionality for Tolerogenic Dendritic Cells and Regulatory Macrophages

Frontiers in Immunology, 2018
The last years have witnessed a breakthrough in the development of cell-based tolerance-inducing cell therapies for the treatment of autoimmune diseases and solid-organ transplantation.
Juan Navarro-Barriuso, Juan Navarro-Barriuso, María José Mansilla, María José Mansilla, Eva M. Martínez-Cáceres, Eva M. Martínez-Cáceres   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genetic diversity analysis and DNA fingerprint construction of Zanthoxylum species based on SSR and iPBS markers

BMC Plant Biology
Zanthoxylum is a versatile economic tree species utilized for its spice, seasoning, oil, medicinal, and industrial raw material applications, and it has a lengthy history of cultivation and domestication in China.
Xiaoxi Zhang, Wei Chen, Zhiwu Yang, Chengrong Luo, Weiwei Zhang, Feng Xu, Jiabao Ye, Yongling Liao   +7 more
doaj   +1 more source

Aligning a new reference genetic map of lupinus angustifolius with the genome sequence of the model legume, Lotus japonicus [PDF]

, 2009
We have developed a dense reference genetic map of Lupinus angustifolius (2n = 40) based on a set of 106 publicly available recombinant inbred lines derived from a cross between domesticated and wild parental lines.
Moolhuijzen, P.M., Swiecicki, W., K. Lesniewska, Cowling, W.A., Ellwood, Simon, Matthew N. Nelson, Paula M. Moolhuijzen, S. R. Ellwood, M. Chudy, Oliver, R.P., Simon R. Ellwood, Richard P. Oliver, Wallace A. Cowling, W. A. Cowling, Boersma, J.G., Ellwood, S.R., Magdalena Chudy, Matthew Bellgard, Oliver, Richard, B. Wolko, Chudy, M., Cowling, W., Boersma, J., Nelson, M., R. P. Oliver, J. G. Boersma, Lesniewska, K., Moolhuijzen, P., Bellgard, M., Nelson, M.N., Wolko, B., M. Bellgard, M. N. Nelson, Wolko, B.W., Karolina Lesniewska, Bogdan Wolko, P. M. Moolhuijzen, Jeffrey G. Boersma, W. Swiecicki   +38 more
core   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Genetic variability in the Skyros pony and its relationship with other Greek and foreign horse breeds

Genetics and Molecular Biology, 2011
In Greece, seven native horse breeds have been identified so far. Among these, the Skyros pony is outstanding through having a distinct phenotype. In the present study, the aim was to assess genetic diversity in this breed, by using different types of ...
Elisabeth Bömcke, Nicolas Gengler, E. Gus Cothran   +2 more
doaj  

Satellyptus: analysis and database of microsatellites from ESTs of Eucalyptus

Genetics and Molecular Biology, 2005
The main goal of our research was to search for SSRs in the Eucalyptus EST FORESTs database (using a software for mining SSR-motifs). With this objective, we created a database for cataloging Eucalyptus EST-derived SSRs, and developed a bioinformatics ...
Paulo Cezar Ceresini, Cristina Lacerda Soares Petrarolha Silva, Robson Fernando Missio, Elaine Costa Souza, Carlos Norberto Fischer, Ivan Rizzo Guillherme, Ivo Gregorio, Eloiza Helena Tajara da Silva, Regina Maria Barreto Cicarelli, Marco Túlio Alves da Silva, José Fernando Garcia, Gustavo Arbex Avelar, Laercio Ribeiro Porto Neto, André Ricardo Marçon, Maurício Bacci Junior, Danyelle Cristine Marini   +15 more
doaj   +1 more source