Results 51 to 60 of about 1,070,803 (312)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Genetic diversity and population structure of Ascochyta rabiei from the western Iranian Ilam and Kermanshah provinces using MAT and SSR markers

open access: yes, 2010
Knowledge of genetic diversity in A. rabiei provides different levels of information that are important in the management of crop germplasm resources. Gene flow on a regional level indicates a significant potential risk for the regional spread of novel ...
Ellwood, S.R.   +19 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Characterisation of the Latvian and Swedish Sweet and Sour Cherry Genetic Resources [PDF]

open access: yes, 2010
A wide diversity of cherry varieties are collected in the Latvian and Swedish genetic resources collections, which consists of landraces and selections of local breeders, adapted to the local climate and growing conditions (winter hardy and disease ...
Lacis, Gunars
core  

Behavioral and Genetic Markers of Sleepiness [PDF]

open access: yesJournal of Clinical Sleep Medicine, 2011
Neurobehavioral responses to acute total and chronic partial sleep deprivation occur in healthy adults and are particularly evident in vigilant attention performance. There are large inter-individual differences in the degree of cognitive deficits--such differences are manifested in proportionality between the mean and variance as sleep loss progresses.
Namni, Goel, David F, Dinges
openaire   +2 more sources

Molecular diagnosis of visceral leishmaniasis from blood samples using different genetic markers: A simple, sensitive and less invasive diagnostic approach

open access: yesPractical Laboratory Medicine
Visceral leishmaniasis (VL), or kala-azar, is a deadly disease with high fatality rates if diagnosis and treatment are delayed. Diagnosis is often delayed due to symptoms that mimic other conditions.
Harish Kumar Shah   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A fast and cost-effective approach to develop and map EST-SSR markers: oak as a case study [PDF]

open access: yes, 2010
Background: Expressed Sequence Tags (ESTs) are a source of simple sequence repeats (SSRs) that can be used to develop molecular markers for genetic studies.
Ikaran, Ziortza   +75 more
core   +1 more source

Psoriasis and Psoriatic Arthritis—Associated Genes, Cytokines, and Human Leukocyte Antigens

open access: yesMedicina
In recent years, research has intensified in exploring the genetic basis of psoriasis (PsO) and psoriatic arthritis (PsA). Genome-wide association studies (GWASs), including tools like ImmunoChip, have significantly deepened our understanding of disease ...
Marek Zalesak   +2 more
doaj   +1 more source

AFRICAN SWINE FEVER VIRUS: USE OF GENETIC MARKERS IN ANALYSIS OF ITS ROUTES OF SPREAD

open access: yesВетеринария сегодня, 2019
At present no effective measures for specific prevention and treatment of African swine fever have been developed. The control strategy for the disease is designed for rapid diagnosis of infected animals with subsequent slaughter and decontamination ...
A. Mazloum   +3 more
doaj   +1 more source

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