Results 111 to 120 of about 1,070,803 (312)

Molecular markers, analysis and the population genetics of parasites

, 2002
In this study different molecular techniques are contrasted (RAPD's, allozyme, sequencing mtDNA, sequencing ribosomal spacers) and appropriate analytical methods (allelic and infinite-sites approaches; inbreeding and coalescent models) used for ...
Constantine, Clare Colleen
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic markers of sex in waterfowl

, 1987
The article summarizes the theory and practice of using genetic markers of sex in waterfowl (goose and duck) production.
Zharkova, I P, Bondarenko, Yuri V., Romanov, Michael N   +2 more
core  

Genetic erosion in crops: concept, research results and challenges

, 2010
The loss of variation in crops clue to the modernization of agriculture has been described as genetic erosion The current paper discusses the different views that exist on the concept of genetic erosion in crops Genetic erosion of cultivated diversity is
Visser, L., Wouw, M.J., van de, Kik, C., van Treuren, R., Hintum, T.J.L., van, van Hintum, T.J.L., van de Wouw, M.J., Treuren, R., van   +7 more
core   +1 more source

Análisis de la variabilidad genética de la colección colombiana de musáceas usando marcadores isoenzimáticos Analysis of the genetic variability of colombian collection of Musaceae using isozyme markers

Acta Agronómica, 2011
La Colección Colombiana de Musáceas (CCM) es la única a nivel mundial que representa un alto valor por ser la que posee introducciones andinas de altura (> 1500 m.s.n.m.).
Martha C Giraldo, Gustavo A Ligarreto, Gerardo Cayón, Constanza Melo   +3 more
doaj  

Genotyping by Amplicon Sequencing (GBAS) With Newly Developed SSR and EPIC Markers Reveals Structure in Populations of the Green Toad (Bufotes viridis) Across Rural and Urban Environments

Ecology and Evolution
Microsatellites (SSRs) are reliable markers for population genetic analyses but often suffer from null alleles caused by mutations in primer binding sites.
Vincent Kendlbacher, Yoko Philipina Krenn, Thapasya Vijayan, Christina Rupprecht, Magdalena Spießberger, Manuel Curto, Lukas Landler, Harald Meimberg   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Populational genetic structure of free-living maned wolves (Chrysocyon brachyurus) determined by proteic markers

Brazilian Journal of Biology
Electrophoretic analysis of presumptive twenty gene loci products was conducted in hemolisates and plasma samples of twenty-eight maned wolves (Chrysocyon brachyurus) from an area in northeastern São Paulo State, Brazil. The area sampled was divided into
P. S. R. De Mattos, M. A. Del Lama, R. H. Toppa, A. R. Arno Rudi Schwantes   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source