Results 81 to 90 of about 5,022,316 (352)
PLoS ONE, 2014 Studies of pharmacogenomics-related traits are increasingly being performed to identify loci that affect either drug response or susceptibility to adverse drug reactions.
V. Bonifaz-Peña +13 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013 The features of forming of dermatoglyphics of feet are compared for sportsmen and people, which do not go in for sports. In researches took part 209 men and 198 women in age 17-19 years, which did not go in for systematic sports.
L.P. Serhiyenko, V.M. Lyshevska
doaj
Serum microRNAs as peripheral markers of primary aldosteronism
Frontiers in EndocrinologyBackgroundPrimary aldosteronism (PA) is the principal cause of secondary hypertension; it leads to significantly elevated cardiovascular morbidity and mortality, but only a fraction of its cases ever get detected, partially due to diagnostic procedures ...
Nikita Makhnov +9 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Potential Biological and Genetic Links Between Dementia and Osteoporosis: A Scoping Review
GeriatricsBackground: The biological mediators for the epidemiologic overlap between osteoporosis and dementia are unclear. We undertook a scoping review of clinical studies to identify genetic and biological factors linked with these degenerative conditions ...
Abayomi N. Ogunwale +4 more
doaj +1 more source
THE INFLUENCE OF MARKERS CSN3 AND ETH10 ON MILK PRODUCTION PARAMETERS IN CZECH PIED CATTLE [PDF]
Journal of Central European Agriculture, 2005 There were observed milk production parameters in 5506 daughters of 37 Czech Pied cattle sires in our study. Sires were genotyped for markers CSN3 and ETH10.
Jitka KUČEROVÁ +7 more
doaj
Arquivos Brasileiros de Cardiologia, 2009 FUNDAMENTO: A síndrome da deleção 22q11.2 é a mais freqüente síndrome de microdeleção humana. O fenótipo é altamente variável e caracterizado por defeito cardíaco conotruncal, dismorfias faciais, insuficiência velofaríngea, dificuldade de aprendizagem e ...
Sintia Iole Nogueira Belangero +5 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source