Results 171 to 180 of about 1,005,916 (291)

Genetic Networks

, 2022
Materna, Stefan C, Woo, Stephanie
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Integrative transcriptomics and phenotyping uncover genetic networks controlling fruit quality in two strawberries (<i>Fragaria × ananassa</i>). [PDF]

Front Plant Sci
Chen Y, Liu H, Jiang T, Song K, Zhang X, Zhang M, Yao H, Duan X, Duan M, Rao MJ.   +9 more
europepmc   +1 more source

NR4A3 and CCL20 clusters dominate the genetic networks in CD146⁺ blood cells during acute myocardial infarction in humans. [PDF]

Eur J Med Res, 2021
Wang YH, Li CX, Stephenson JM, Marrelli SP, Kou YM, Meng DZ, Wu T.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Regulatory Genetic Networks by microRNAs: Exploring Genomic Signatures in Cervical Cancer. [PDF]

Biomedicines
Pérez-Plasencia C, Orbe-Orihuela YC, Méndez-Herrera A, Deas J, Gómez-Cerón C, Jiménez-Wences H, Ortiz-Ortiz J, Fernández-Tilapa G, Clemente-Soto AF, Parra-Unda JR, Velarde-Felix JS, Rodríguez-Dorantes M, Peralta-Zaragoza O.   +12 more
europepmc   +1 more source

Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency. [PDF]

EMBO J, 2021
Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, Beyer A, Leeb M.   +16 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Exploring the Genetic Networks of HLB Tolerance in Citrus: Insights Across Species and Tissues. [PDF]

Plants (Basel)
Machado R, Moschen S, Conti G, González SA, Rivarola M, Gómez C, Hopp HE, Fernández P.   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source