Results 11 to 20 of about 1,005,916 (291)

Identification of Genetic Networks [PDF]

open access: yesGenetics, 2004
AbstractIn this report, we propose the use of structural equations as a tool for identifying and modeling genetic networks and genetic algorithms for searching the most likely genetic networks that best fit the data. After genetic networks are identified, it is fundamental to identify those networks influencing cell phenotypes.
Momiao, Xiong, Jun, Li, Xiangzhong, Fang
openaire   +3 more sources

The balance of weak and strong interactions in genetic networks. [PDF]

open access: yesPLoS ONE, 2011
Genetic interactions are being quantitatively characterized in a comprehensive way in several model organisms. These data are then globally represented in terms of genetic networks. How are interaction strengths distributed in these networks?
Juan F Poyatos
doaj   +1 more source

Reverse engineering of genetic networks with Bayesian networks [PDF]

open access: yes, 2003
This paper provides a brief introduction to learning Bayesian networks from gene-expression data. The method is contrasted with other approaches to the reverse engineering of biochemical networks, and the Bayesian learning paradigm is briefly described ...
Husmeier, D.
core   +1 more source

Network growth models and genetic regulatory networks [PDF]

open access: yesPhysical Review E, 2006
8 pages with 7 eps figures; uses revtex4.
Foster, D. V.   +2 more
openaire   +3 more sources

Multiple genetic interaction experiments provide complementary information useful for gene function prediction. [PDF]

open access: yesPLoS Computational Biology, 2012
Genetic interactions help map biological processes and their functional relationships. A genetic interaction is defined as a deviation from the expected phenotype when combining multiple genetic mutations.
Magali Michaut, Gary D Bader
doaj   +1 more source

Genes and chromosomes: control of development

open access: yesAnais da Academia Brasileira de Ciências, 2004
The past decade has witnessed immense progress in research into the molecular basis behind the developmental regulation of genes. Sets of genes functioning under hierarchical control have been identified, evolutionary conserved systems of genes effecting
Oleg Serov, Irina Serova
doaj   +1 more source

Systematic analysis of bypass suppression of essential genes

open access: yesMolecular Systems Biology, 2020
Essential genes tend to be highly conserved across eukaryotes, but, in some cases, their critical roles can be bypassed through genetic rewiring. From a systematic analysis of 728 different essential yeast genes, we discovered that 124 (17%) were ...
Jolanda van Leeuwen   +18 more
doaj   +1 more source

Parallel implementation of stochastic simulation for large-scale cellular processes [PDF]

open access: yes, 2005
Experimental and theoretical studies have shown the importance of stochastic processes in genetic regulatory networks and cellular processes. Cellular networks and genetic circuits often involve small numbers of key proteins such as transcriptional ...
Burrage, K., Tian, T.
core   +2 more sources

Network-based analysis of the sphingolipid metabolism in hypertension

open access: yesFrontiers in Genetics, 2015
Common diseases like essential hypertension or diabetes mellitus are complex as they are polygenic in nature, such that each genetic variation only has a small influence on the disease.
Mogens eFenger
doaj   +1 more source

Rapid cell-free forward engineering of novel genetic ring oscillators

open access: yeseLife, 2015
While complex dynamic biological networks control gene expression in all living organisms, the forward engineering of comparable synthetic networks remains challenging. The current paradigm of characterizing synthetic networks in cells results in lengthy
Henrike Niederholtmeyer   +6 more
doaj   +1 more source

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