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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
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Widespread Rewiring of Genetic Networks upon Cancer Signaling Pathway Activation.
Cell Syst, 2018 Billmann M +4 more
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Science, 1995
The interactions of biological macromolecules and the flow of regulatory information that controls development, behavior, and homeostasis can be considered a genetic network. The nodes in such networks are genes or their RNA and protein products. The connections are the regulatory and physical interactions among the RNAs, proteins, and cis-regulatory ...
Loomis, William F., Sternberg, Paul W.
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The interactions of biological macromolecules and the flow of regulatory information that controls development, behavior, and homeostasis can be considered a genetic network. The nodes in such networks are genes or their RNA and protein products. The connections are the regulatory and physical interactions among the RNAs, proteins, and cis-regulatory ...
Loomis, William F., Sternberg, Paul W.
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Pharmacogenomics, 2002
The inference of genetic interactions from measured expression data is one of the most challenging tasks of modern functional genomics. When successful, the learned network of regulatory interactions yields a wealth of useful information. An inferred genetic network contains information about the pathway to which a gene belongs and which genes it ...
E P, van Someren +3 more
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The inference of genetic interactions from measured expression data is one of the most challenging tasks of modern functional genomics. When successful, the learned network of regulatory interactions yields a wealth of useful information. An inferred genetic network contains information about the pathway to which a gene belongs and which genes it ...
E P, van Someren +3 more
openaire +2 more sources
Genetic Regulatory Networks and Neural Networks
2009The discussion on the neural networks paradigm casted a bright light on the notion of network and on what we may define as the “dynamical systems approach”. The rebounds of this emphasis involved, during the years, the most disparate scientific areas, such as biology, social sciences and artificial life, contributing to reinforce ...
SERRA, Roberto +2 more
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2015
It has been observed that much of the diversity in the natural world can be traced to three features of developmental biology, namely, interactions between gene products, the temporal nature of gene expression, and shifts in the location of gene expression [32]. The first item highlights the significance of feedback loops in developmental processes. In
Anthony Brabazon +2 more
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It has been observed that much of the diversity in the natural world can be traced to three features of developmental biology, namely, interactions between gene products, the temporal nature of gene expression, and shifts in the location of gene expression [32]. The first item highlights the significance of feedback loops in developmental processes. In
Anthony Brabazon +2 more
openaire +2 more sources
Science's STKE, 2004
Understanding the topology of genetic networks and their functional order may enable human geneticists to develop new approaches for identifying disease genes associated with complex traits. Tong et al. (see the Perspective by Hartwell) have used double mutants to examine the network of genetic interactions in yeast.
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Understanding the topology of genetic networks and their functional order may enable human geneticists to develop new approaches for identifying disease genes associated with complex traits. Tong et al. (see the Perspective by Hartwell) have used double mutants to examine the network of genetic interactions in yeast.
openaire +2 more sources
Parallel Computing, 2001
We show how random Boolean networks, a well-known model of the interaction among genes within a living cell, can be generalized by relaxing the Boolean approximation, therefore defining a class of continuous genetic networks, and by explicitly describing gene--chemical interactions.
SERRA, Roberto +2 more
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We show how random Boolean networks, a well-known model of the interaction among genes within a living cell, can be generalized by relaxing the Boolean approximation, therefore defining a class of continuous genetic networks, and by explicitly describing gene--chemical interactions.
SERRA, Roberto +2 more
openaire +2 more sources
Science, 1995
In the caption of the photograph accompanying the Perspective "Genetic networks" by W. F. Loomis and Paul W. Sternberg (4 Aug., p. 649), the name of the sculpture should have been given as "Mozart I," and the sculptor, Kenneth Snelson, should have been mentioned.
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In the caption of the photograph accompanying the Perspective "Genetic networks" by W. F. Loomis and Paul W. Sternberg (4 Aug., p. 649), the name of the sculpture should have been given as "Mozart I," and the sculptor, Kenneth Snelson, should have been mentioned.
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Genetic programming with genetic regulatory networks
Proceedings of the 15th annual conference on Genetic and evolutionary computation, 2013Evolutionary Algorithms (EA) approach differently from nature the genotype - phenotype relationship, and this view is a recurrent issue among researchers. Recently, some researchers have started exploring computationally the new comprehension of the multitude of regulatory mechanisms that are fundamental in both processes of inheritance and of ...
Rui L. Lopes, Ernesto Costa
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