Results 121 to 130 of about 418,825 (313)
Genetic parameters represent fundamental measures that describe the genetic architecture of traits within populations. These parameters encompass a range of characteristics, including heritability, genetic correlation, and repeatability, crucial for understanding evolutionary processes, selective breeding, and genetic diversity conservation ...
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
AnimalsObjective: The study aimed to investigate the effects of castration on performance, carcass characteristics, and meat quality in sheep, as well as explore the expression of key genes related to metabolic pathways and muscle growth following castration ...
Shahab Ur Rehman +9 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Genetic relationships between calving interval and body condition score conditional on milk yield [PDF]
, 2002 Body condition score (BCS) is a useful tool in assessing the energy status of dairy cattle. Previous research has shown that it is heritable and genetically correlated to reproductive performance.
Coffey, M.P. +3 more
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A demonstration of the utility of fractional experimental design for finding optimal genetic algorithm parameter settings [PDF]
, 2004 This paper demonstrates that the use of sparse experimental design in the development of the structure for genetic algorithms, and hence other computer programs, is a particularly effective and efficient strategy.
Whitfield, R.I. +3 more
core +1 more source
Poultry Science: This study aimed to estimate genetic parameters for feeding behavior (FB) traits and to assess their genetic relationship with performance traits in group-housed broilers. In total, 99,472,151 visits were recorded for 95,711 birds between 2017 and 2022
Anderson A.C. Alves +5 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The parameter-less genetic algorithm in practice [PDF]
, 2008 The parameter-less genetic algorithm was introduced a couple of years ago as a way to simplify genetic algorithm operation by incorporating knowledge of parameter selection and population sizing theory in the genetic algorithm itself.
David E. Goldberg B, O G. Lobo A
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