Results 131 to 140 of about 418,825 (313)

Juvenile growth performance and associated genetic parameters in common carp, Cyprinus carpio cultured in 8 ppt inland saline groundwater

Aquatic Living Resources
The degraded soils unfit for primary agricultural crops can be utilised for inland saline aquaculture of saline-tolerant species. In India, a genetic improvement program for developing a faster-growing, saline-tolerant strain of common carp has been ...
Raghul Ravi, Pathan Mujahidkhan A., Gjerde Bjarne, Singh Angom Lenin, Misra Archana, P.S Nagaraja, Prakash Satya   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Genetic algorithm optimization for blind channel identification with higher order cumulant fitting [PDF]

, 1997
—An important family of blind equalization algorithms identify a communication channel model based on fitting higher order cumulants, which poses a nonlinear optimization prob-lem.
Y. Wu, S. Mclaughlin, S. Chen, Wu, Y., Chen, S., McLaughlin, S.   +5 more
core  

Genetic parameter estimation and fine-mapping of milk-production traits and somatic cell score in Chinese Simmental cattle

Journal of Dairy Science
: Chinese Simmental cattle serve as an important dual-purpose breed in sustainable livestock systems. Despite their economic value, the genetic architecture underlying milk-production traits in this breed under temperate conditions remains poorly ...
Chunxiao Dong, Peipei Ma, Yongjie Tang, Haoqi Han, Siqian Chen, Jiazi Yang, Zhigang Sun, Wei Wang, Ying Yu, Shengli Li   +9 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Genetic Variability and Trait Associations in Ethiopian and Exotic Lentil (Lens culinaris) Germplasm

International Journal of Plant Biology
Yield is a complex trait influenced by multiple components and their genetic behavior. Therefore, this study was designed to understand the complex nature of yield by uncovering relationships among traits and estimating the genetic parameters of lentil ...
Nigussie Kefelegn, Solomon Benor, Gizachew Haile Gidamo, Asnake Fikre, Ming Pei You, Martin J. Barbetti   +5 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Impact of Heat Stress on Milk Yield, Milk Fat-to-Protein Ratio, and Conception Rate in Thai–Holstein Dairy Cattle: A Phenotypic and Genetic Perspective

Animals
Heat stress severely affects dairy cattle production and reproduction performances in tropical regions. Genetic selection to maintain adequate yield and reproductive performance while enhancing their ability to withstand heat is essential for improving ...
Wuttigrai Boonkum, Watcharapong Teawyoneyong, Vibuntita Chankitisakul, Monchai Duangjinda, Sayan Buaban   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source