Results 51 to 60 of about 3,837,457 (288)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Combined genetic algorithm optimization and regularized orthogonal least squares learning for radial basis function networks

, 1999
The paper presents a two-level learning method for radial basis function (RBF) networks. A regularized orthogonal least squares (ROLS) algorithm is employed at the lower level to construct RBF networks while the two key learning parameters, the ...
Luk, B.L., Wu, Y., Chen, S.
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Genetic Parameters for Fertility of Dairy Bulls

Journal of Dairy Science, 1988
Genetic parameters for male fertility and fertility ratings of AI bulls were obtained by analyzing 298,013 service records of cows with successive calving records. Cows were mated to 746 service bulls, which were progeny of 126 sires. The model for variance component estimation accounted for fixed effects of herd-year-seasons, sire of the service bull,
K, Nadarajah, E B, Burnside, L R, Schaeffer   +2 more
openaire   +2 more sources

Genetic parameters for stayability in Murrah buffaloes [PDF]

Journal of Dairy Research, 2010
In order to contribute to the breeding programmes of Asian water buffalo, the aim of this study was to analyse the influence of genetic effects in the stayability of Murrah dairy buffaloes. The stayability trait (ST) was defined as the female's ability to stay in the herd for one (ST1), two (ST2), three (ST3), four (ST4), five (ST5) or six years (ST6 ...
Galeazzi, Priscilla M., Mercadante, Maria E. Z., Silva, Josineudson A. I. I. V., Aspilcueta-Borquis, Rusbel R., de Camargo, Gregorio M. F., Tonhati, Humberto   +5 more
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A semi-automated design of instance-based fuzzy parameter tuning for metaheuristics based on decision tree induction [PDF]

, 2015
Two main concepts are established in the literature for the Parameter Setting Problem (PSP) of metaheuristics: Parameter Tuning Strategies (PTS) and Parameter Control Strategies (PCS).
Ries, Jana, Beullens, Patrick
core   +1 more source

Genetic Parameters of Bovine Serum Immunoglobulins

Journal of Dairy Science, 1985
Radial immunodiffusion techniques were used to determine serum concentrations of immunoglobulins G1, G2, M, and A in 1,293 daughters of 282 Holstein-Friesian sires from 31 herds in southwestern Ontario, Canada. Mean serum immunoglobulin concentrations (mg/100 ml) were 2,163, 2,409, 531, and 107 for immunoglobulins G1, G2, M, and A, respectively.
K E, Mazengera, B W, Kennedy, E B, Burnside, B N, Wilkie, J H, Burton   +4 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source