Results 61 to 70 of about 947,581 (290)

Darwin Meets Einstein: LISA Data Analysis Using Genetic Algorithms

, 2006
This work presents the first application of the method of Genetic Algorithms (GAs) to data analysis for the Laser Interferometer Space Antenna (LISA). In the low frequency regime of the LISA band there are expected to be tens of thousands galactic binary
C. Darwin, J. Holland, J. Lucas Reddinger, Jeff Crowder, Neil J. Cornish, V. M. Lipunov   +5 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Genetic Analysis of Persistency for Milk Fat Yield in Iranian Buffaloes (Bubalus bubalis)

Frontiers in Genetics, 2021
This study aimed to estimate heritabilities and genetic trends for different persistency measures for milk fat yield and their genetic correlations with 270-day milk yield in Iranian buffaloes.
Mohammad Ali Nazari, Navid Ghavi Hossein-Zadeh, Abdol Ahad Shadparvar, Davood Kianzad   +3 more
doaj   +1 more source

Genetic parameters for stayability in Murrah buffaloes [PDF]

Journal of Dairy Research, 2010
In order to contribute to the breeding programmes of Asian water buffalo, the aim of this study was to analyse the influence of genetic effects in the stayability of Murrah dairy buffaloes. The stayability trait (ST) was defined as the female's ability to stay in the herd for one (ST1), two (ST2), three (ST3), four (ST4), five (ST5) or six years (ST6 ...
Galeazzi, Priscilla M., Mercadante, Maria E. Z., Silva, Josineudson A. I. I. V., Aspilcueta-Borquis, Rusbel R., de Camargo, Gregorio M. F., Tonhati, Humberto   +5 more
openaire   +3 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Genetic parameters for dairy calf and replacement heifer wellness traits and their association with cow longevity and health indicators in Holstein cattle

Journal of Dairy Science, 2022
: High mortality and involuntary culling rates cause great economic losses to the worldwide dairy cattle industry. However, there is low emphasis on wellness traits in replacement animals (dairy calves and replacement heifers) during their development ...
Hailiang Zhang, Kai Wang, Tao An, Lei Zhu, Yao Chang, Wenqi Lou, Lin Liu, Gang Guo, Aoxing Liu, Guosheng Su, Luiz F. Brito, Yachun Wang   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fractal Characterizations of MAX Statistical Distribution in Genetic Association Studies

, 2009
Two non-integer parameters are defined for MAX statistics, which are maxima of $d$ simpler test statistics. The first parameter, $d_{MAX}$, is the fractional number of tests, representing the equivalent numbers of independent tests in MAX.
Azzalini A., Heisenberg W., Mao J., Press W. H., Sham P., Sokal R. K., Thomas D. C., Weir B. S.   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Genetic aspects of immunoglobulins and cyclophilin A in milk as potential indicators of mastitis resistance in Holstein cows

Journal of Dairy Science
: Mastitis is one of the most frequent and costly diseases affecting dairy cattle. Natural antibodies (immunoglobulins) and cyclophilin A (CyPA), the most abundant member of the family of peptidyl prolyl cis/trans isomerases, in milk may serve as ...
Yoshinobu Uemoto, Teppei Katsura, Yuma Endo, Koutaro Tanaka, Tao Zhuang, Megumi Urakawa, Toshimi Baba, Gaku Yoshida, Haifei Wang, Haruki Kitazawa, Hitoshi Shirakawa, Takehiko Nakamura, Tomonori Nochi, Hisashi Aso   +13 more
doaj   +1 more source