Results 91 to 100 of about 10,561,542 (295)

Genomic Relationship Matrix for Correcting Pedigree Errors in Breeding Populations: Impact on Genetic Parameters and Genomic Selection Accuracy

, 2014
Quantitative genetic analyses aim to estimate genetic parameters and breeding values to select superior parents, families, and individuals. For these estimates a relationship matrix derived from the pedigree typically is used in a mixed model framework ...
P. Muñoz, Marcio F. R. Resende, D. Huber, Tania Quesada, M. Resende, D. Neale, J. Wegrzyn, M. Kirst, Gary F. Peter   +8 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

An analysis of the genetic relationship between udder health and udder conformation traits in South African Jersey cows

Animal, 2009
A multi-trait animal model was used to estimate genetic parameters among lactation somatic cell score (SCS) and udder-type traits in South African Jersey cattle, through restricted maximum likelihood (REML) procedures.
B. Dube, K. Dzama, C.B. Banga, D. Norris
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Assessment of Piglet Vitality by Farmers—Validation of A Scoring Scheme and Estimation of Associated Genetic Parameters

Animals, 2019
Maternal breeds for sows have been bred for high prolificacy during recent decades. Although large litters may be beneficial for economic efficiency, pre-weaning mortality is increased.
Katharina Schodl, Regine Revermann, Christoph Winckler, Birgit Fuerst-Waltl, Christine Leeb, Alfons Willam, Peter Knapp, Christina Pfeiffer   +7 more
doaj   +1 more source

The evolution of phenotypes and genetic parameters under preferential mating

Ecology and Evolution, 2014
This article extends and adds more realism to Lande's analytical model for evolution under mate choice by using individual-based simulations in which females sample a finite number of males and the genetic architecture of the preference and preferred ...
D. Roff, D. Fairbairn
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Research Regarding Heritability and Repeatability Coefficients of some Milk Production Traits from Farms in Moldavian Region

Scientific Papers Animal Science and Biotechnologies, 2023
Aim of this study was estimation of two genetic parameters: heritability and repeatability, for five milk production traits. Data used in current paper consisted from phenotypic information from 998 cows with 1897 yield records.
Nicoleta Roşca (Dulgheru), Ştefan Creangă, Mihaela Ivancia   +2 more
doaj  

Seleção de genitores de Eucalyptus grandis e de Eucalyptus urophylla para produção de híbridos interespecíficos utilizando REML/BLUP e informação de divergência genética Selection of Eucalyptus grandis and Eucalyptus urophylla parents for the production of interespecific hybrids using REML/BLUP and genetic diversity data

Revista Árvore, 2007
Foram avaliadas 363 progênies de meios-irmãos de Eucalyptus urophylla e de 245 progênies de meios-irmãos de E. grandis, visando à seleção de genitores para a produção de híbridos interespecíficos em cruzamentos controlados em dialelo circulante, com base
Maria das Graças de Barros Rocha, Ismael Eleotério Pires, Rodrigo Barros Rocha, Aloísio Xavier, Cosme Damião Cruz   +4 more
doaj   +1 more source