Results 101 to 110 of about 284,664 (210)

Differential Immune Cell Infiltration in Eosinophilic and Non‐Eosinophilic CRS: Correlations With Clinical, Endoscopic, and Radiological Findings

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The pathogenesis of inflammation in eosinophilic chronic rhinosinusitis (ECRS) and non‐eosinophilic chronic rhinosinusitis (NECRS) remains poorly understood. This study aimed to assess immune cell infiltration within the sinonasal microenvironment in these conditions.
Katarzyna Czerwaty, Katarzyna Piszczatowska, Mirosław J. Szczepański, Natalia Jermakow, Nils Ludwig, Karolina Dżaman   +5 more
wiley   +1 more source

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

Animal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera, Abeer Abdullah Alghamdi, Mesfer Al‐Shahrani, Reem M. Al‐Gahtani, Bashayer Saad Alghamdi, Gaffar Sarwar Zaman, Mohammed Abdul Rasheed, Hassan Al‐Shehri, Lana Al‐qhtani, Syed Parween Ali, Umme Hani, Talha Bin Emran   +11 more
wiley   +1 more source

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

Annals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner, Eliza Honybun, Melanie Bahlo, Karen L. Oliver, Ingrid E. Scheffer   +4 more
wiley   +1 more source

Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor. [PDF]

Genome Med
Wegert J, Appenzeller S, Treger TD, Streitenberger H, Ziegler B, Bausenwein S, Vokuhl C, Parks C, Jüttner E, Gramlich S, Ernestus K, Warman SW, Fuchs J, Hubertus J, von Schweinitz D, Fröhlich B, Jorch N, Knöfler R, Friedrich C, Corbacioglu S, Frühwald MC, Pekrun A, Schneider DT, Faber J, Stursberg J, Metzler M, Welter N, Pritchard-Jones K, Graf N, Furtwängler R, Behjati S, Gessler M.   +31 more
europepmc   +1 more source

Exploring the promoter regions of cancer predisposition genes in patients with triple-negative breast cancer reveals the presence of rare germline variants. [PDF]

Oncologist
Palleschi M, Virga A, Scarpi E, Fonzi E, Musolino A, Merloni F, Sarti S, Danesi R, Ravegnani M, Casadei C, Sirico M, Gianni C, Maltoni R, Bravaccini S, Calistri D, Arcangeli V, Zampiga V, Cangini I, Bandini E, Mannozzi F, Falcini F, Martinelli G, De Giorgi U, Ulivi P, Tedaldi G.   +24 more
europepmc   +1 more source

Genetic predisposition in sarcomas: clinical implications and management. [PDF]

EClinicalMedicine
Connolly EA, Boye K, Bonvalot S, Kratz CP, Leithner A, Malkin D, Messiou C, Miah AB, Pantziarka P, Timmermann B, van der Graaf WTA, Thomas DM, Stacchiotti S.   +12 more
europepmc   +1 more source

Prevalence of Genetic Variants Associated with Atrial Fibrillation Risk in the Asymptomatic Young Adult Population. [PDF]

Medicina (Kaunas)
Murugan M, Ravikumar S, Ganesh I, Vetriselvan Y, Priyadharshini A, Ballambattu VB.   +5 more
europepmc   +1 more source

A new spin on chemotaxonomy: Using non‐proteogenic amino acids as a test case

Applications in Plant Sciences, EarlyView.
Abstract Premise Specialized metabolites serve various roles for plants and humans. Unlike core metabolites, specialized metabolites are restricted to certain plant lineages; thus, in addition to their ecological functions, specialized metabolites can serve as diagnostic markers of plant lineages.
Makenzie Gibson, William Thives Santos, Alan R. Oyler, Lucas Busta, Craig A. Schenck   +4 more
wiley   +1 more source

Establishment of a comprehensive set of fact sheets for cancer predisposition genes for medical oncologists practicing cancer genome profiling. [PDF]

Int J Clin Oncol
Matsukawa M, Tomozawa C, Nakamura Y, Fujisawa T, Kimura K, Hiraoka Y, Yamashita R, Kosugi S, Sakurai A, Imoto I, Nishigaki M, Hirata M, Kuwata T, Yoshino T.   +13 more
europepmc   +1 more source

Gout and NLRP3 inflammasome biology

Arthritis &Rheumatology, Accepted Article.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilisation, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal‐induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source