Results 11 to 20 of about 191,359 (264)

Genetic Predisposition to Thrombophilia in Inflammatory Bowel Disease [PDF]

Journal of Clinical Gastroenterology, 2011
Inflammatory bowel disease (IBD) is linked to a definite risk of thromboembolic events (TE), but data on the role of prothrombotic genetic mutations are conflicting.Fourteen genetic factors involved in TE pathogenesis were investigated in a homogeneous cohort of Sicilian patients with IBD with and without history of TE and in healthy controls.
Cappello, M, GRIMAUDO, Stefania, BRAVATA', Ivana, RANDAZZO, Claudia, PIPITONE, Rosaria Maria, LICATA, Anna, CAMMA', Calogero, CRAXI, Antonio   +7 more
openaire   +3 more sources

Risk of newly developed atrial fibrillation by alcohol consumption differs according to genetic predisposition to alcohol metabolism: a large-scale cohort study with UK Biobank

BMC Medicine, 2023
Background The predictive relationship between mild-to-moderate alcohol consumption and the risk of incident atrial fibrillation (AF) remains controversial.
Chan Soon Park, Jaewon Choi, JungMin Choi, Kyung-Yeon Lee, Hyo-Jeong Ahn, Soonil Kwon, So-Ryoung Lee, Eue-Keun Choi, Soo Heon Kwak, Seil Oh   +9 more
doaj   +1 more source

Genetic Predisposition to Cardiovascular Diseases [PDF]

International Journal of Human Genetics, 2001
Extensive clinical and statistical studies have identified several factors that increase the risk of heart disease, heart attack and stroke. Major risk factors are those that are associated with a significant increase in the risk of heart and blood vessel disease (CVD).
openaire   +1 more source

Periodontal disease: a genetic perspective

Brazilian Oral Research, 2012
Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge.
Mario Taba Jr, Sergio Luis Scombatti de Souza, Viviane Casagrande Mariguela   +2 more
doaj   +1 more source

Glutathione S-transferase T1 and M1 polymorphisms and risk of thyroid neoplasms [PDF]

Archive of Oncology, 2003
Background: In order to test the possibility of association between GSTT1 and M1 (glutathione S-transferase) null allele variant, in which the entire gene is absent, and the risk of TCO (thyroid carcinoma with cell oxyphilia), the case-control study was ...
Stankov Karmen, Landi Stefano, Volante Marco, Papotti Mauro   +3 more
doaj   +1 more source

Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing.

PLoS ONE, 2017
Genetic predisposition increases the risk of familial breast cancer. Recent studies indicate that genetic predisposition for familial breast cancer can be ethnic-specific.
Yeong C Kim, Amr S Soliman, Jian Cui, Mohamed Ramadan, Ahmed Hablas, Mohamed Abouelhoda, Nehal Hussien, Ola Ahmed, Abdel-Rahman Nabawy Zekri, Ibrahim A Seifeldin, San Ming Wang   +10 more
doaj   +1 more source

Assessment of Familial Predisposition Through Parental Inquiry in Undescended Testis Cases

Haseki Tıp Bülteni
Aim: Non-syndromic cryptorchidism, also referred to as undescended testis (UDT), represents a developmental abnormality occurring in early childhood, the underlying cause of which remains unclear.
Kenan Yalcin, Engin Kolukcu, Fatih Firat
doaj   +1 more source

Genetic cause of pulmonary veno-occlusive disease

Lung India, 2022
Pulmonary veno-occlusive disease (PVOD) is an important cause of pulmonary arterial hypertension (PAH) and is classified under idiopathic cause of PAH. Over a period of time, PVOD has been studied in detail in the western countries and various diagnostic
Kaustubh Mohite, Anil Kumar Sapare
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Prediction of sepsis-related outcomes in neonates through systematic genotyping of polymorphisms in genes for innate immunity and inflammation: a narrative review and critical perspective

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Neonatal sepsis is associated with premature birth and maternal infection. Large-scale studies seek to define markers that identify neonates at risk of developing sepsis.
Juliana Kilesse Carvalho, Daniella Batalha Moore, Ricardo Alves Luz, Pedro Paulo Xavier-Elsas, Maria Ignez Capella Gaspar-Elsas   +4 more
doaj   +1 more source