Results 31 to 40 of about 319,093 (308)

Periodontal disease: a genetic perspective

Brazilian Oral Research, 2012
Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge.
Mario Taba Jr, Sergio Luis Scombatti de Souza, Viviane Casagrande Mariguela   +2 more
doaj   +1 more source

Glutathione S-transferase T1 and M1 polymorphisms and risk of thyroid neoplasms [PDF]

Archive of Oncology, 2003
Background: In order to test the possibility of association between GSTT1 and M1 (glutathione S-transferase) null allele variant, in which the entire gene is absent, and the risk of TCO (thyroid carcinoma with cell oxyphilia), the case-control study was ...
Stankov Karmen, Landi Stefano, Volante Marco, Papotti Mauro   +3 more
doaj   +1 more source

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura, D’Amato, Andrea, Fedele, Francesco, Mancone, Massimo, Netti, Lucrezia, Palmirotta, Raffaele, Pucci, Mariateresa, Severino, Paolo, Volterrani, Maurizio   +8 more
core   +2 more sources

A continuum of psychosis, one human gene, and not much else - the case for homogeneity [PDF]

, 1995
The contention of this paper is that psychoses are not a collection of separate and unrelated diseases, but a set of diverse expressions of a single underlying entity.
Crow, Prof TJ
core   +1 more source

Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey [PDF]

, 2020
Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their
Baccolini, V., Barnhoorn, F., D'Andrea, E., de Vito, C., Marco, M. D., Marzuillo, C., Paget, D. Z., Pitini, E., Rosso, A., Unim, B., Villari, P.   +10 more
core   +2 more sources

Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]

, 2016
Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS, Gilmour, KC, House, IG, Layton, M, Panoskaltsis, N, Sohal, M, Trapani, JA, Voskoboinik, I   +7 more
core   +1 more source

Investigating the association of rs2910164 with cancer predisposition in an Irish cohort. [PDF]

, 2017
IntroductionMicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA).
Bell, M, Guerin, C, Kerin, MJ, Lowery, AJ, McVeigh, TP, McVeigh, UM, Miller, N, Mulligan, RJ, Owens, PW, Quill, DS, Sebag, F, Weidhaas, JB   +11 more
core   +3 more sources

Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing.

PLoS ONE, 2017
Genetic predisposition increases the risk of familial breast cancer. Recent studies indicate that genetic predisposition for familial breast cancer can be ethnic-specific.
Yeong C Kim, Amr S Soliman, Jian Cui, Mohamed Ramadan, Ahmed Hablas, Mohamed Abouelhoda, Nehal Hussien, Ola Ahmed, Abdel-Rahman Nabawy Zekri, Ibrahim A Seifeldin, San Ming Wang   +10 more
doaj   +1 more source

Genetic Predisposition to Cardiovascular Diseases [PDF]

International Journal of Human Genetics, 2001
Extensive clinical and statistical studies have identified several factors that increase the risk of heart disease, heart attack and stroke. Major risk factors are those that are associated with a significant increase in the risk of heart and blood vessel disease (CVD).
openaire   +1 more source

Assessment of Familial Predisposition Through Parental Inquiry in Undescended Testis Cases

Haseki Tıp Bülteni
Aim: Non-syndromic cryptorchidism, also referred to as undescended testis (UDT), represents a developmental abnormality occurring in early childhood, the underlying cause of which remains unclear.
Kenan Yalcin, Engin Kolukcu, Fatih Firat
doaj   +1 more source