Results 31 to 40 of about 208,174 (208)

Genetic factors associated with the predisposition to late onset Alzheimer's disease

, 2021
Background Alzheimer's disease is a progressive, irreversible neurodegenerative disorder characterized by loss of memory and cognitive skills. More than 90% of cases are sporadic and have later age of onset.
Pehlivan, Sacide, Orman, Mehmet, Kumral, Emre, ONAY, HÜSEYİN, Aslan, Gulcin Itirli, Ozkinay, Ferda, Durmaz, Burak, Cogulu, Ozgur, DURMAZ, ASUDE   +8 more
core   +1 more source

Obesity in young adults: The differentiated impact of LEP, LEPR, and FTO gene variants [PDF]

Genetics and Molecular Biology
Obesity is a global public health issue, increasingly affecting young adults. Its association with other diseases highlights the urgency of developing prevention strategies. Genetic factors play a significant role in susceptibility to obesity, making the
Leandro da Rocha Lima, Roberta Luisa Barbosa Leal, Marcos Vinícius Guimarães Soares, Gabriela Eduardo França de Araujo, Ana Beatriz Martins Topciu Fonseca, Alessandra dos Santos Ribeiro, Beatriz de Abreu Lopes de Azevedo, Marcelo Ribeiro-Alves, Kenia Balbi El-Jaick   +8 more
doaj   +2 more sources

Genetic Predisposition to Cardiovascular Diseases [PDF]

International Journal of Human Genetics, 2001
Extensive clinical and statistical studies have identified several factors that increase the risk of heart disease, heart attack and stroke. Major risk factors are those that are associated with a significant increase in the risk of heart and blood vessel disease (CVD).
openaire   +1 more source

Assessment of Familial Predisposition Through Parental Inquiry in Undescended Testis Cases

Haseki Tıp Bülteni
Aim: Non-syndromic cryptorchidism, also referred to as undescended testis (UDT), represents a developmental abnormality occurring in early childhood, the underlying cause of which remains unclear.
Kenan Yalcin, Engin Kolukcu, Fatih Firat
doaj   +1 more source

Genetic predisposition to higher blood pressure increases coronary artery disease risk.

, 2013
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field.Hypertension is a risk factor for coronary artery disease.
Pencina, Michael J, Vasan, Ramachandran S, Nelson, Christopher P, Ziegler, Andreas, Laaksonen, Reijo, Thorsteinsdottir, Unnur, Jansen, Henning, Boerwinkle, Eric, Thompson, John R, Erdmann, Jeanette, Newton-Cheh, Christopher, Holm, Hilma, Hengstenberg, Christian, McPherson, Ruth, Reilly, Muredach P, Assimes, Themistocles L, Deloukas, Panos, Loley, Christina, Roberts, Robert, Samani, Nilesh J, Schunkert, Heribert, Peters, Annette, Lieb, Wolfgang, Hall, Alistair S, Stewart, Alexandre F R, Kathiresan, Sekar, König, Inke R   +26 more
core   +1 more source

Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing.

PLoS ONE, 2017
Genetic predisposition increases the risk of familial breast cancer. Recent studies indicate that genetic predisposition for familial breast cancer can be ethnic-specific.
Yeong C Kim, Amr S Soliman, Jian Cui, Mohamed Ramadan, Ahmed Hablas, Mohamed Abouelhoda, Nehal Hussien, Ola Ahmed, Abdel-Rahman Nabawy Zekri, Ibrahim A Seifeldin, San Ming Wang   +10 more
doaj   +1 more source

[Histiocytic sarcoma in the Swiss population of Bernese mountain dogs: a retrospective study of its genetic predisposition]

, 2006
A retrospective study to evaluate the genetic predisposition for histiocytic sarcoma in the Swiss population of purebred Bernese mountain dogs identified 51 histologically confirmed cases between 1997 and 2003.
Hauser, B, Flückiger, M, Welle, M, Voegeli, E, Dolf, G   +4 more
core   +1 more source

Genetic Predisposition to Recurrent Aphthous Stomatitis

, 2017
Background: Recurrent aphthous stomatitis (RAS), one of the most common diseases of the oral mucosa, is characterized by the formation of painful oral erosions or even ulcers.
L. Hollá, L. Izakovičová Hollá, P. Bořilová Linhartová, S. Valová, P. Linhartová   +4 more
core   +1 more source

Prediction of sepsis-related outcomes in neonates through systematic genotyping of polymorphisms in genes for innate immunity and inflammation: a narrative review and critical perspective

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Neonatal sepsis is associated with premature birth and maternal infection. Large-scale studies seek to define markers that identify neonates at risk of developing sepsis.
Juliana Kilesse Carvalho, Daniella Batalha Moore, Ricardo Alves Luz, Pedro Paulo Xavier-Elsas, Maria Ignez Capella Gaspar-Elsas   +4 more
doaj   +1 more source

Genetic predisposition to metabolic dysfunction-associated fatty liver disease

Zdorovʹe Rebenka
The literature review highlights the issue of genetic risk factors associated with the development of metabolic dysfunction-associated fatty liver disease. Human genetic examinations revealed 132 genes among which 32 loci are strongly associated with the
O.E. Abaturov, A.O. Nikulina
doaj   +1 more source