Results 11 to 20 of about 88,056,303 (299)

Genetic markers of children asthma: predisposition to disease course variants

Вавиловский журнал генетики и селекции, 2023
Asthma is a heterogeneous and often difficult to treat condition that results in a disproportionate cost to healthcare systems. Children with severe asthma are at increased risk for adverse outcomes including medication-related side effects, life ...
M. V. Smolnikova, Ed. W. Kasparov, M. A. Malinchik, K. V. Kopylova   +3 more
doaj   +1 more source

Genetic and Epigenetic Etiology of Inflammatory Bowel Disease: An Update

, 2022
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and remission of the disease. The etiology of IBD is not fully understood. Many studies point to the presence of genetic, immunological, environmental, and microbiological
Rafał Filip, Sokal, Aneta, Magdalena Zielińska, Sara Jarmakiewicz-Czaja, Aneta Sokal, Jarmakiewicz-Czaja, Sara, Filip, Rafał, Zielińska, Magdalena   +7 more
core   +1 more source

Self-reported cancer family history is a useful tool for identification of individuals at risk of hereditary cancer predisposition syndrome at primary care centers in middle-income settings: a longitudinal study [PDF]

Genetics and Molecular Biology, 2016
Analysis of cancer family history (CFH) offers a low-cost genetic tool to identify familial cancer predisposition. In middle-income settings, the scarcity of individual records and database-linked records hinders the assessment of self-reported CFH ...
Milena Flória-Santos, Luís Carlos Lopes-Júnior, Larissa de Melo Alvarenga, Mayara Segundo Ribeiro, Victor Evangelista de Faria Ferraz, Lucila Castanheira Nascimento, Gabriela Pereira-da-Silva   +6 more
doaj   +3 more sources

Modifier genes and Lynch syndrome: some considerations

Hereditary Cancer in Clinical Practice, 2022
Lynch Syndrome (LS) is a highly variable entity with some patients presenting at very young ages with malignancy whereas others may never develop a malignancy yet carry an unequivocal genetic predisposition to disease.
Rodney J. Scott
doaj   +1 more source

Genetic predisposition of cholesterol gallstone disease

Annals of Hepatology, 2006
Gallstone disease (GSD) is the result of the interaction between genetic and environmental factors and it is a major disease cause of surgery with high costs to health systems. Worldwide prevalence varies according to the ethnic population suggesting that high prevalence of GSD in certain ethnic groups is due to the presence of genetic factors ...
Alejandro Hernández-Nazará, Fátima Curiel-López, Erika Martínez-López, Zamira Hernández-Nazará, Arturo Panduro   +4 more
openaire   +3 more sources

Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB As Novel Risk Loci for Systemic Sclerosis [PDF]

, 2011
Systemic sclerosis (SSc) is an orphan, complex, inflammatory disease affecting the immune system and connective tissue. SSc stands out as a severely incapacitating and life-threatening inflammatory rheumatic disease, with a largely unknown pathogenesis ...
P. Amouyel, MELCHERS I, Cusi, D., Amouye, Philippe, Jerome Avouac, Melchers, Inga, Salvi Erika, Müller, Martina, ALLANORE Y, Damjanov Nemanja, Meyer Oliver, HACHULLA E, Nemanja Damjanov, Hunzelmann Nicolas, I. Melchers, H.-Erich Wichmann, Wichmann, H.-E., Ulf Müller-Ladner, Lambert, J.C., Ruiz, B., AMOUYEL P, Munnich, A., Riemekasten, Gabriella, Cracowski Jean-Luc, Distler, J.H., AVOUAC J, CONTI C, Hachulla Eric, Dupuy, Anne-Marie, Dieude, Philippe, AIRO P, Munnich Arnold, Caramaschi, Paola, Avouac, Jerome, Nicolas Hunzelmann, Inga Melchers, Lambert J. C, Allanore, Y., C. Boileau, Conti, Costanza, Diot, Elisabeth, Lambert Jean-Charles, A. M. Dupuy, O. Meyer, Yannick Allanore, Avouac, J., Martinez, Maria, Ruiz Barbara, Otylia Kowal Bielecka, Wichmann, H-Erich, Luc Letenneur, J. Avouac, P. Caramaschi, Mouthon Luc, Wipff, J., Wichmann, H.-Erich, Dieudé Philippe, C. Conti, Meyer, O., E. Hachulla, M. Müller, Mouthon, L., Arnold Munnich, Avouac Jérôme, Damjanov, Nemanja, Gabriele Valentini, Valentini, G., Müller-Ladner Ulf, Caramaschi Paola, Müller, M., Tiev, Kiet, Martinez, M., Meyer, Oliver, MARTINEZ M., Kowal-Bielecka, O., H. Erich Wichmann, Distler, Jorg, H. W., A. Munnich, Matucci-Cerinic Marco, Dupuy Anne Marie, László Czirjak, G. Valentini, DAMJANOV N, MEYER O, Kahan, Andre, Melchers Inga, RICCIERI V, Saad, M., Jorg H W Distler, Cusi Daniele, Ruiz, Barbara, Kahan André, Martina Muller, E. Salvi, WIPFF J, E. Diot, Distler J, Müller Martina, CARAMASCHI P, DIOT E, Erika Salvi, J. C. Lambert, HUNZELMANN N, Matucci-Cerinic, M., Boileau, Catherine, Dieudé, P., Airo, P., Cusi, Daniele, Riccieri, Valeria, Müller-Ladner, U., J. Wipff, L. Czirják, Distler, Jorg H. W., Hachulla, E., Czirjak, Laszlo, Czijak L, Y. Allanore, MUNNICH A, Mohamad Saad, Czirják, L., Wipff, Julien, K. Tiev, L. Letenneur, Letenneur, Luc, Maria Martinez, Conti Costanza, Airo Paolo, Kowal-Bielecka, Otylia, N. Damjanov, MÜLLER LADNER U, SALVI E, WICHMANN HE, Valentini Gabriele, Jorg H. W. Distler, Paolo Airo, DUPUY AM, Valentini G, CUSI D, MÜLLER M, Mouthon, Luc, J. L. Cracowski, Damjanov, N., LAMBERT JC, Distler Jorg H. W., H-Erich Wichmann, P. Dieudé, Diot, E., MATUCCI CERINIC, Marco, Paola Caramaschi, Valentini, Gabriele, Hachulla, Eric, Jean Luc Cracowski, Tiev Kiet, CRACOWSKI JL, Airo, Paolo, Costanza Conti, Jean-Charles Lambert, RUIZ B, Daniele Cusi, Martinez Maria, Valeria Riccieri, M. Matucci Cerinic, MATUCCI CERINIC M, Eric Hachulla, H. E. Wichmann, Lambert, Jean-Charles, Wichmann, Heinz-Erich, Tiev, K., Kiet Tiev, Catherine Boileau, MOUTHON L, Riemekasten, G., Jean Charles Lambert, L. Mouthon, Caramaschi, P., Marco Matucci-Cerinic, SAAD M, B. Ruiz, Riemekasten Gabriella, J. H. Distler, BOILEAU C, Boileau Catherine, Philippe Amouyel, Riccieri Valeria, Munnich, Arnold, Cracowski, Jean-Luc, Gabriella Riemekasten, DIEUDÉ P, N. Hunzelmann, Saad Mohamad, Letenneur Luc, Czirják László, Allanore, Yannick, Philippe Dieude, Julien Wipff, Müller-Ladner, Ulf, KOWAL BIELECKA O, LETENNEUR L, Kowal-Bielecka Otylia, Elisabeth Diot, G. Riemekasten, KAHAN A, Wichmann H.-Erich, Salvi, E., Matucci-Cerinic, Marco, Dupuy, A.M., D.M. Cusi, Oliver Meyer, U. Müller Ladner, Hunzelmann, Nicolas, Allanore Yannick, Wipff Julien, Cracowski, J.L., Saad, Mohamad, Barbara Ruiz, RIEMEKASTEN G, O. Kowal Bielecka, Conti, C., M. Martinez, Jean-Luc Cracowski, P. Airo, CZIRJÁK L, Amouyel, Philippe, Letenneur, L., Salvi, Erika, DISTLER JH, Amouyel, P., Distler, Jorg,, Luc Mouthon, V. Riccieri, Hunzelmann, N., Ulf Muller Ladner, TIEV K, Dupuy, Anne Marie, Diot Elisabeth, Kahan, A., Riccieri, V., Marco Matucci Cerinic, André Kahan, Boileau, C., M. Saad, A. Kahan, Anne Marie Dupuy, Amouyel Philippe, Otylia Kowal-Bielecka, Melchers, I.   +245 more
core   +2 more sources

Genetic predisposition to higher blood pressure increases coronary artery disease risk. [PDF]

, 2013
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field.Hypertension is a risk factor for coronary artery disease.
Pencina, Michael J, Vasan, Ramachandran S, Nelson, Christopher P, Ziegler, Andreas, Laaksonen, Reijo, Thorsteinsdottir, Unnur, Jansen, Henning, Boerwinkle, Eric, Thompson, John R, Erdmann, Jeanette, Newton-Cheh, Christopher, Holm, Hilma, Hengstenberg, Christian, McPherson, Ruth, Reilly, Muredach P, Assimes, Themistocles L, Deloukas, Panos, Loley, Christina, Roberts, Robert, Samani, Nilesh J, Schunkert, Heribert, Peters, Annette, Lieb, Wolfgang, Hall, Alistair S, Stewart, Alexandre F R, Kathiresan, Sekar, König, Inke R   +26 more
core   +1 more source

Genetic predisposition and the variable course of infectious diseases

Deutsches Ärzteblatt international, 2022
Contact with a pathogen is followed by variable courses of infectious disease, which are only partly explicable by classical risk factors. The susceptibility to infection is variable, as is the course of disease after infection. In this review, we discuss the extent to which this variation is due to genetic factors of the affected individual (the host).
Axel, Schmidt, Ana M, Groh, Julia S, Frick, Maria J G T, Vehreschild, Kerstin U, Ludwig   +4 more
openaire   +2 more sources

The expressivist objection to prenatal testing : the experiences of families living with genetic disease [PDF]

, 2014
The expressivist objection to prenatal testing is acknowledged as a significant critique of prenatal testing practices most commonly advanced by disability rights supporters.
Felicity Kate Boardman, Boardman, Felicity Kate, Boardman, Felicity K.   +2 more
core   +1 more source

Venous Thromboembolism in Kidney Diseases and Genetic Predisposition

Kidney Diseases, 2022
<b><i>Background:</i></b> Many renal diseases have been associated with profound clinical effects on thrombosis. To our knowledge, patients with nephrotic syndrome (NS) and chronic kidney disease (CKD) display an elevated risk of vein thrombosis, which is among the common causes of mortality in patients with renal diseases.
Tingting Wu, Liang V. Tang, Yu Hu
openaire   +3 more sources