Results 11 to 20 of about 198,180 (264)

Genetic markers of children asthma: predisposition to disease course variants

open access: yesВавиловский журнал генетики и селекции, 2023
Asthma is a heterogeneous and often difficult to treat condition that results in a disproportionate cost to healthcare systems. Children with severe asthma are at increased risk for adverse outcomes including medication-related side effects, life ...
M. V. Smolnikova   +3 more
doaj   +1 more source

Genetic predisposition of cholesterol gallstone disease

open access: yesAnnals of Hepatology, 2006
Gallstone disease (GSD) is the result of the interaction between genetic and environmental factors and it is a major disease cause of surgery with high costs to health systems. Worldwide prevalence varies according to the ethnic population suggesting that high prevalence of GSD in certain ethnic groups is due to the presence of genetic factors ...
Alejandro Hernández-Nazará   +4 more
openaire   +3 more sources

Genetic Predisposition and Inflammatory Bowel Disease [PDF]

open access: yesGastroenterology Research, 2013
Published reports demonstrated finding of different susceptible mutant alleles in association with inflammatory bowel disease (CD/UC) in diseased individuals from different populations. It was then assumed that the existence of different associated mutant alleles in subjects with inflammatory bowel disease from different populations means different ...
openaire   +2 more sources

Venous Thromboembolism in Kidney Diseases and Genetic Predisposition

open access: yesKidney Diseases, 2022
<b><i>Background:</i></b> Many renal diseases have been associated with profound clinical effects on thrombosis. To our knowledge, patients with nephrotic syndrome (NS) and chronic kidney disease (CKD) display an elevated risk of vein thrombosis, which is among the common causes of mortality in patients with renal diseases.
Tingting Wu, Liang V. Tang, Yu Hu
openaire   +3 more sources

Genetic predisposition and the variable course of infectious diseases

open access: yesDeutsches Ärzteblatt international, 2022
Contact with a pathogen is followed by variable courses of infectious disease, which are only partly explicable by classical risk factors. The susceptibility to infection is variable, as is the course of disease after infection. In this review, we discuss the extent to which this variation is due to genetic factors of the affected individual (the host).
Axel, Schmidt   +4 more
openaire   +2 more sources

Genetic Predisposition to Respiratory Diseases: Infiltrative Lung Diseases [PDF]

open access: yesRespiration, 2006
The availability of high-throughput genotyping and large collaborative clinical networks creating well-characterized patient populations with DNA repositories has facilitated genome-wide scans and candidate gene studies to identify susceptibility alleles for the development of interstitial lung disease.
Mark P, Steele, Kevin K, Brown
openaire   +2 more sources

Risk of newly developed atrial fibrillation by alcohol consumption differs according to genetic predisposition to alcohol metabolism: a large-scale cohort study with UK Biobank

open access: yesBMC Medicine, 2023
Background The predictive relationship between mild-to-moderate alcohol consumption and the risk of incident atrial fibrillation (AF) remains controversial.
Chan Soon Park   +9 more
doaj   +1 more source

Glutathione S-transferase T1 and M1 polymorphisms and risk of thyroid neoplasms [PDF]

open access: yesArchive of Oncology, 2003
Background: In order to test the possibility of association between GSTT1 and M1 (glutathione S-transferase) null allele variant, in which the entire gene is absent, and the risk of TCO (thyroid carcinoma with cell oxyphilia), the case-control study was ...
Stankov Karmen   +3 more
doaj   +1 more source

Genetic predisposition in nonalcoholic fatty liver disease [PDF]

open access: yesClinical and Molecular Hepatology, 2017
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when severe clinical forms, including nonalcoholic steatohepatitis (NASH), cirrhosis and even hepatocellular carcinoma, occur, they result in worsening
Sookoian, Silvia Cristina   +1 more
openaire   +4 more sources

Periodontal disease: a genetic perspective

open access: yesBrazilian Oral Research, 2012
Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge.
Mario Taba Jr   +2 more
doaj   +1 more source

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