Results 11 to 20 of about 942,879 (267)
Genetics of Drug Resistance [PDF]
Summary: Drug resistance in epilepsy affects about a third of patients and is an important clinical problem, associated with increased morbidity and mortality. It is important to consider carefully the definition of drug resistance. Recent interest in the field has focused on the potential molecular mechanisms underlying drug resistance. Environmental
openaire +2 more sources
Background MicroRNAs are small non-coding RNAs that are involved in various biological processes including insect development. Anopheles stephensi serves as primary vector of malaria parasite in Asia and exhibits holometabolous life cycle that involves ...
Shanu Jain +4 more
doaj +1 more source
Genetics of Antimicrobial Resistance
Antimicrobial resistant strains of bacteria are an increasing threat to animal and human health. Resistance mechanisms to circumvent the toxic action of antimicrobials have been identified and described for all known antimicrobials currently available for clinical use in human and veterinary medicine. Acquired bacterial antibiotic resistance can result
H, Harbottle +3 more
openaire +2 more sources
Anopheles gambiae Genome Conservation as a Resource for Rational Gene Drive Target Site Selection
The increase in molecular tools for the genetic engineering of insect pests and disease vectors, such as Anopheles mosquitoes that transmit malaria, has led to an unprecedented investigation of the genomic landscape of these organisms.
Nace Kranjc +3 more
doaj +1 more source
Highly pathogenic avian influenza viruses (HPAIVs) cause severe systemic disease and high mortality rates in chickens, leading to a huge economic impact in the poultry sector. However, some chickens are resistant to the disease.
Albert Perlas +12 more
doaj +1 more source
Using resistant cultivars is a common approach to managing blackleg of canola/rapeseed caused by Leptosphaeria maculans (Lm). Quantitative resistance (QR), as opposed to major-gene resistance, is of interest because it is generally more durable, due to ...
Michelle Hubbard, Chun Zhai, Gary Peng
doaj +1 more source
Genetics of Resistance to Tetraethyllead [PDF]
A Drosophila melanogaster population was exposed for 25 generations to 60 pg tetraethyllead per gram of medium. Selection over this period resulted in an increase in fecundity, hatchability and larva-to-adult viability. Chromosome assay showed that response in these traits was generally under additive genetic control in conformity with existing results
openaire +2 more sources
Creating genetic resistance to HIV [PDF]
HIV/AIDS remains a chronic and incurable disease, in spite of the notable successes of combination antiretroviral therapy. Gene therapy offers the prospect of creating genetic resistance to HIV that supplants the need for antiviral drugs. In sight of this goal, a variety of anti-HIV genes have reached clinical testing, including gene-editing enzymes ...
John C, Burnett +2 more
openaire +2 more sources
Herbaceous grafting is a propagation method largely used in solanaceous and cucurbit crops for enhancing their agronomic performances especially under (a)biotic stress conditions.
Mariateresa Cardarelli +4 more
doaj +1 more source
Crop resilience measures must be strengthened in response to the global climate impact. Temperature stress exacerbates the impact on crop growth and grain yield, threatening the sustainability of grapevine production and dependent wine industries. Grape (
Vivek Yadav +9 more
doaj +1 more source

