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Genetics of antiepileptic drug resistance
Current Opinion in Neurology, 2009Drug resistance is an important clinical problem in epilepsy, affecting a substantial number of patients globally. Mechanisms underlying drug resistance need to be understood to develop rational therapies. Genetics offers one route to better understanding, and thus potentially treating, drug resistance.Several important advances in epilepsy genomics ...
Sanjay M, Sisodiya, Carla, Marini
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Genetics of insulin resistance
Experimental and Clinical Endocrinology & Diabetes, 2009Even among young, healthy individuals, there is more than a 10-fold variation in insulin sensitivity; however, taken in combination, all the known modifiers of insulin sensitivity - including obesity and a variety of environmental factors - explain less than one third of this variation.
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The genetics and genomics of insecticide resistance
Trends in Genetics, 2004Uploaded by Plazi for TaxoDros. We do not have abstracts.
Delourme, Régine +4 more
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Genetic resistance to leukemia
ScienceA genome-wide association study identifies a genetic variant that reduces the risk of ...
Francisco, Caiado, Markus G, Manz
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Genetics and Resistance to Tuberculosis
Annals of Internal Medicine, 1992Recent observations strongly suggest a significant role for genetic factors in innate resistance to infection by Mycobacterium tuberculosis. This relation was discovered in a study of tuberculosis in Arkansas nursing homes and was supported by data from three outbreaks of tuberculosis in two prisons.
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Genetic Engineering and Resistance to Viruses
2002International ...
Fuchs, Marc, Gonsalves, D.
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Comparative genetics of warfarin resistance
Hämostaseologie, 2014SummaryWarfarin and other 4-hydroxycoumarinbased oral anticoagulants targeting vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) are administered to humans, mice and rats with different purposes in mind – to act as pesticides in high-dosage baits for killing rodents, but also to save lives when administered in low dosages as antithrombotic ...
J, Oldenburg +4 more
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The genetic underground of antibiotic resistance
Science, 2021The silent role and clinical relevance of metabolic mutations in antibiotic resistance begin to be ...
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Genetics of Plant Virus Resistance
Annual Review of Phytopathology, 2005Genetic resistance to plant viruses has been used for at least 80 years to control agricultural losses to viral diseases. To date, hundreds of naturally occurring genes for resistance to plant viruses have been reported from studies of both monocot and dicot crops, their wild relatives, and the plant model, Arabidopsis.
Byoung-Cheorl, Kang +2 more
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Genetically Controlled Resistance to Viruses
1983Historically, the first demonstrations of the existence of host genes that could control resistance to disease induced by an animal virus were reported independently by Lynch and Hughes (1) and Webster and Clow (2) in 1936. Subsequently, a number of other genes have been identified in various strains of inbred mice, each of which confers resistance to ...
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