Results 21 to 30 of about 7,418,451 (334)

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

Genetics of Drug Resistance [PDF]

Epilepsia, 2005
Summary:  Drug resistance in epilepsy affects about a third of patients and is an important clinical problem, associated with increased morbidity and mortality. It is important to consider carefully the definition of drug resistance. Recent interest in the field has focused on the potential molecular mechanisms underlying drug resistance. Environmental
openaire   +2 more sources

Mitigating Aflatoxin Contamination in Groundnut through A Combination of Genetic Resistance and Post-Harvest Management Practices

Toxins, 2019
Aflatoxin is considered a “hidden poison” due to its slow and adverse effect on various biological pathways in humans, particularly among children, in whom it leads to delayed development, stunted growth, liver damage, and liver cancer.
M. Pandey, Rakesh Kumar, A. Pandey, P. Soni, S. S. Gangurde, H. Sudini, J. Fountain, Boshou Liao, H. Desmae, P. Okori, Xiaoping Chen, Huifang Jiang, Venugopal Mendu, H. Falalou, S. Njoroge, J. Mwololo, B. Guo, W. Zhuang, Xingjun Wang, Xuanqiang Liang, R. Varshney   +20 more
semanticscholar   +1 more source

Dynamic expression of miRNAs across immature and adult stages of the malaria mosquito Anopheles stephensi

Parasites & Vectors, 2015
Background MicroRNAs are small non-coding RNAs that are involved in various biological processes including insect development. Anopheles stephensi serves as primary vector of malaria parasite in Asia and exhibits holometabolous life cycle that involves ...
Shanu Jain, Vandita Rana, Adak Tridibes, Sujatha Sunil, Raj K Bhatnagar   +4 more
doaj   +1 more source

A Novel Root-Knot Nematode Resistance QTL on Chromosome Vu01 in Cowpea. [PDF]

, 2019
The root-knot nematode (RKN) species Meloidogyne incognita and M. javanica cause substantial root system damage and suppress yield of susceptible cowpea cultivars.
Guo, Yi-Ning, Huynh, Bao L, Lo, Sassoum, Matthews, William C, Muñoz-Amatriaín, Maria, Ndeve, Arsenio D, Roberts, Philip A, Santos, Jansen RP   +7 more
core   +2 more sources

Evolved polygenic herbicide resistance in Lolium rigidum by low-dose herbicide selection within standing genetic variation [PDF]

, 2012
The interaction between environment and genetic traits under selection is the basis of evolution. In this study, we have investigated the genetic basis of herbicide resistance in a highly characterized initially herbicide-susceptible Lolium rigidum ...
Darmency H., Falconer D. S, Lande R., Sokal R. R.   +3 more
core   +1 more source

Mobile Genetic Elements Associated with Antimicrobial Resistance

Clinical Microbiology Reviews, 2018
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an increasing major health care problem around the world.
S. Partridge, S. Kwong, N. Firth, S. Jensen   +3 more
semanticscholar   +1 more source

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]

, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker, Andrew N. Rycroft, Brendan W. Wren, Clinical and Laboratory Standards Institute, de Groot, Duncan J. Maskell, Janine T. Bossé, Jon Rogers, Lucy A. Weinert, Matt T. G. Holden, Olusegun Oshota, Paul R. Langford, Roberto Fernandez Crespo, Roy R. Chaudhuri, Stephanie Walker, Susanna M. Williamson, Tom Atherton, Yanwen Li   +17 more
core   +4 more sources

Genetics of Antimicrobial Resistance

Animal Biotechnology, 2006
Antimicrobial resistant strains of bacteria are an increasing threat to animal and human health. Resistance mechanisms to circumvent the toxic action of antimicrobials have been identified and described for all known antimicrobials currently available for clinical use in human and veterinary medicine. Acquired bacterial antibiotic resistance can result
H, Harbottle, S, Thakur, S, Zhao, D G, White   +3 more
openaire   +2 more sources

Mitochondrial dysfunction, insulin resistance and potential genetic implications.

Endocrinology, 2020
Insulin resistance, IR, is fundamental to the development type 2 diabetes (T2D) and is present in most prediabetic (preDM) individuals. IR has both heritable and environmental determinants centered on energy storage and metabolism.
Panjamaporn Sangwung, K. Petersen, G. Shulman, J. Knowles   +3 more
semanticscholar   +1 more source