Results 51 to 60 of about 4,995,654 (311)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Genetic architecture of rainbow trout survival from egg to adult [PDF]

, 2010
Survival from birth to a reproductive adult is a challenge that only robust individuals resistant to a variety of mortality factors will overcome. To assess whether survival traits share genetic architecture throughout the life cycle, we estimated ...
Paananen, T., Quiton, C., Vehvilainen, H., Kuukka-Anttila, H., Koskinen, H., Kause, A.   +5 more
core   +1 more source

Population genomics of selectively neutral genetic structure and herbicide resistance in UK populations of Alopecurus myosuroides [PDF]

, 2020
BACKGROUND Alopecurus myosuroides (blackgrass) is a major weed in Europe with known resistance to multiple herbicide modes of action. In the UK, there is evidence that blackgrass has undergone a range expansion.
Dixon, A., David Comont, Gancho T Slavov, Comont, D., Neve, P., Slavov, G., Andrea Dixon, Paul Neve   +7 more
core   +1 more source

Comparative Genetics of Resistance to Viruses [PDF]

The American Journal of Human Genetics, 1998
Human beings differ widely in their responses to virus infections. Viruses may induce barely discernible symptoms in some patients and severe, life-threatening illness in others. These differences reflect both the complex, intimate, and multifaceted nature of virus-host interactions and the variables that can influence these interactions.
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers [PDF]

, 2011
Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool to comprehensively explore gene regulatory networks and to investigate the effects of genetic variation at the molecular level.
Polonikov, Alexey, Wichmann, Heinz-Erich, Fabian J. Theis, Stephan Weidinger, Wichmann Heinz Erich, Gieger, C., Ried, Janina S., Christian Gieger, Krumsiek, J., Karsten Suhre, Prehn, C., Kirstin Mittelstrass, Heinz Erich Wichmann, Polonikov, A., Weidinger, S., Alexey Polonikov, Werner Roemisch-Margl, Yu Zhonghao, Theis, F.J., Wang-Sattler, R., Jan Krumsiek, Ried Janina S., Yu, Z., Gieger Christian, Mittelstrass, Kirstin, Wichmann, H.-E., Polonikov Alexey, Illig, T., Fabian J Theis, Peters, Annette, Illig Thomas, Mittelstrass Kirstin, Zhonghao Yu, Theis, Fabian J., Peters Annette, Kronenberg Florian, Florian Kronenberg, Jerzy Adamski, Annette Peters, Wang-Sattler, Rui, Krumsiek, Jan, Theis Fabian J., Peters, A., Krumsiek Jan, Illig, Thomas, Roemisch-Margl Werner, Wang-Sattler Rui, Meitinger, Thomas, Adamski, Jerzy, Ried, J.S., Cornelia Prehn, Thomas Illig, Römisch-Margl, W., Suhre Karsten, Gieger, Christian, Weidinger, Stephan, Weidinger Stephan, Suhre, K., Roemisch-Margl, Werner, Kronenberg, Florian, Yu, Zhonghao, Adamski Jerzy, Thomas Meitinger, Meitinger, T., Prehn, Cornelia, Rui Wang-Sattler, Kronenberg, F., Janina S. Ried, Prehn Cornelia, Adamski, J., Mittelstraß, K., Suhre, Karsten, Janina S Ried, Meitinger Thomas, Mittelstrass, K;Ried, JS;Yu, Z;Krumsiek, J;Gieger, C;Prehn, C;Roemisch-Margl, W;Polonikov, A;Peters, A;Theis, FJ;Meitinger, T;Kronenberg, F;Weidinger, S;Wichmann, HE;Suhre, K;Wang-Sattler, R;Adamski, J;Illig, T, Mittelstraß, K. ; Ried, J.S. ; Yu, Z. ; Krumsiek, J. ; Gieger, C. ; Prehn, C. ; Römisch-Margl, W. ; Polonikov, A. ; Peters, A. ; Theis, F.J. ; Meitinger, T. ; Kronenberg, F. ; Weidinger, S. ; Wichmann, H.-E. ; Suhre, K. ; Wang-Sattler, R. ; Adamski, J. ; Illig, T.   +75 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Research on resistance to sunflower broomrape: an integrated vision

Oilseeds and fats, crops and lipids, 2016
Sunflower broomrape (Orobanche cumana Wallr.) parasitization on sunflower was first observed at the end of the 19th century and has continued since then jeopardizing sunflower cultivation in many areas of Europe and Asia.
Velasco Leonardo, Pérez-Vich Begoña, Fernández-Martínez José M.   +2 more
doaj   +1 more source

Performance- and Resistance-Related Early Responses of Colombian Elite Rubber Tree Genotypes under Low Pressure of South American Leaf Blight: Implications for Disease Management in the Amazon

Plants, 2023
The cultivation of Hevea brasiliensis, the primary commercial source of natural rubber, is strongly impacted by South American leaf blight (SALB) disease, caused by the fungus Pseudocercospora ulei.
Lyda Constanza Galindo-Rodríguez, Armando Sterling, Herminton Muñoz-Ramirez, Jesica Andrea Fonseca-Restrepo   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source